Literature DB >> 324958

Papulacandins, a new family of antibiotics with antifungal activity, I. Fermentation, isolation, chemical and biological characterization of papulacandins A, B, C, D and E.

P Traxler, J Gruner, J A Auden.   

Abstract

Papulacandin, a new antibiotic complex, active against Candida albicans and several other yeasts, was isolated from a strain of Papularia sphaerosperma. The fermentation, isolation, physico-chemical properties and biological activity of the five structurally related papulacandins A, B, C, D and E are reported. Papulacandin B, the main component, was assigned the formula of C47H64O17.

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Year:  1977        PMID: 324958     DOI: 10.7164/antibiotics.30.289

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  11 in total

Review 1.  Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance.

Authors:  M A Ghannoum; L B Rice
Journal:  Clin Microbiol Rev       Date:  1999-10       Impact factor: 26.132

2.  Total Synthesis of (+)-Papulacandin D.

Authors:  Scott E Denmark; Tetsuya Kobayashi; Christopher S Regens
Journal:  Tetrahedron       Date:  2010-06-26       Impact factor: 2.457

3.  Discovery of novel antifungal (1,3)-beta-D-glucan synthase inhibitors.

Authors:  J Onishi; M Meinz; J Thompson; J Curotto; S Dreikorn; M Rosenbach; C Douglas; G Abruzzo; A Flattery; L Kong; A Cabello; F Vicente; F Pelaez; M T Diez; I Martin; G Bills; R Giacobbe; A Dombrowski; R Schwartz; S Morris; G Harris; A Tsipouras; K Wilson; M B Kurtz
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

Review 4.  Astonishing diversity of natural surfactants: 2. Polyether glycosidic ionophores and macrocyclic glycosides.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-03       Impact factor: 1.880

Review 5.  Compounds active against cell walls of medically important fungi.

Authors:  R F Hector
Journal:  Clin Microbiol Rev       Date:  1993-01       Impact factor: 26.132

6.  Lysis of growing cells of Saccharomyces cerevisiae induced by papulacandin B.

Authors:  M Kopecká
Journal:  Folia Microbiol (Praha)       Date:  1984       Impact factor: 2.099

7.  Papulacandin B resistance in budding and fission yeasts: isolation and characterization of a gene involved in (1,3)beta-D-glucan synthesis in Saccharomyces cerevisiae.

Authors:  C Castro; J C Ribas; M H Valdivieso; R Varona; F del Rey; A Duran
Journal:  J Bacteriol       Date:  1995-10       Impact factor: 3.490

8.  In vitro conidial germination in Arthrinium aureum and Arthrinium phaeospermum.

Authors:  Montserrat Agut; María Angeles Calvo
Journal:  Mycopathologia       Date:  2004-05       Impact factor: 2.574

9.  Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis.

Authors:  Akihiro Kitamura; Kazuhiko Someya; Masato Hata; Ryohei Nakajima; Makoto Takemura
Journal:  Antimicrob Agents Chemother       Date:  2008-11-17       Impact factor: 5.191

Review 10.  Antimicrobial Peptides: a New Frontier in Antifungal Therapy.

Authors:  Giuseppe Buda De Cesare; Shane A Cristy; Danielle A Garsin; Michael C Lorenz
Journal:  mBio       Date:  2020-11-03       Impact factor: 7.867

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