Literature DB >> 32495017

Radical hysterectomy for early cervical cancer: what shall we do after the LACC trial?

Peter Hillemanns1, Hermann Hertel2, Rüdiger Klapdor2.   

Abstract

Surgical treatment of cervical cancer has led to one of the greatest controversies in gynecological oncology in recent years. After laparoscopic radical hysterectomy became increasingly widespread worldwide, it lost its importance dramatically when the data from the LACC study were published. In contrast to previous assumptions, there was a significantly reduced survival after laparoscopic hysterectomy compared to the open abdominal procedure. Multiple studies were subsequently published. Some confirm these results some do not. Some consider further studies to be unethical, others point to their own non-randomized results and call for a new LACC study. This article gives an overview of the current data situation and the possible criticisms of the individual studies. And, finally, calls for new RCT's under defined criteria.

Entities:  

Keywords:  Cervical cancer; LACC; Laparoscopy; Radical hysterectomy; Robotic surgery

Year:  2020        PMID: 32495017     DOI: 10.1007/s00404-020-05627-x

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  3 in total

Review 1.  The Future in Standards of Care for Gynecologic Laparoscopic Surgery to Improve Training and Education.

Authors:  Vlad I Tica; Andrei A Tica; Rudy L De Wilde
Journal:  J Clin Med       Date:  2022-04-14       Impact factor: 4.964

Review 2.  Protective operative techniques in radical hysterectomy in early cervical carcinoma and their influence on disease-free and overall survival: a systematic review and meta-analysis of risk groups.

Authors:  Johanna Kampers; E Gerhardt; P Sibbertsen; T Flock; R Klapdor; H Hertel; M Jentschke; P Hillemanns
Journal:  Arch Gynecol Obstet       Date:  2021-05-22       Impact factor: 2.344

3.  Retrospective Analysis of Cervical Cancer Treatment Outcomes: Ten Years of Experience with the Vaginal Assisted Radical Laparoscopic Hysterectomy VARLH.

Authors:  R Wojdat; E Malanowska
Journal:  Biomed Res Int       Date:  2022-01-10       Impact factor: 3.411

  3 in total

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