Ludovica Marzano1,2, Nicolas Thiounn3,4, Helena Pereira5,6, Olivier Pellerin3,7,8, Charles Dariane4, Costantino Del Giudice3,7, Gregory Amouyal9, Carol Dean7,8, Marc Sapoval10,11,12. 1. Vascular and Oncological Interventional Radiology Department Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France. Ludovica.Marzano@eoc.ch. 2. Istituto di Imaging della Svizzera Italiana, Ospedale Regionale Bellinzona e Valli, EOC, Bellinzona, Switzerland. Ludovica.Marzano@eoc.ch. 3. Faculté de Médecine, Université Paris V: René Descartes, Paris, France. 4. Urology Department Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France. 5. Clinical Research Unit Assistance Publique Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France. 6. INSERM U1418, Paris, France. 7. Vascular and Oncological Interventional Radiology Department Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France. 8. INSERM U970, Paris, France. 9. Hôpital Saint Louis, Paris, France. 10. Faculté de Médecine, Université Paris V: René Descartes, Paris, France. marc.sapoval2@aphp.fr. 11. Vascular and Oncological Interventional Radiology Department Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France. marc.sapoval2@aphp.fr. 12. INSERM U970, Paris, France. marc.sapoval2@aphp.fr.
Abstract
INTRODUCTION: The effect of prostate artery embolization (PAE) on male sexual function is currently the subject of debate in the literature. The main purpose of this study was to define changes in all domains of sexual activity after PAE, using the international index of erectile function score (IIEF-15). METHODS: A single-center retrospective study was conducted on 129 patients (mean age of 65.5 ± 7 years), who underwent PAE from February 2014 to January 2017 for symptomatic benign prostatic hyperplasia (BPH). Fifty consecutive patients fulfilling the inclusion criteria were evaluated before and after PAE follow-up using the IIEF-15, IPSS, prostate volume (PV) and cardiovascular risk factor and BPH drugs. The IIEF-15 domains analyzed were: erectile function (EF) ejaculation and orgasm (Ej/O), sexual desire (SD), intercourse satisfaction (IS) and overall satisfaction (OS). A paired sample t test or Wilcoxon signed-rank test was used to compare IIEF-15 between baseline and follow-up. RESULTS: The study showed nonsignificant change in IIEF-15 total score (58.0 ± 13.8 SD; p = 0.71) and the five domains (EF 24.5 ± 7.0 SD, p = 0.82; EJ/O 8.2 ± 2.3 SD, p = 0.50; SD 7.2 ± 2.7 SD, p = 0.57; IS 10.3 ± 3.0 SD, p = 0.77; OS 8.2 ± 2.7 SD; p = 0.11) after PAE. We also found a significant improvement in IPSS score after PAE. CONCLUSION: Based on the IIEF-15 questionnaire, PAE was showed to allow good urinary symptoms results and no deterioration in sexual function.
INTRODUCTION: The effect of prostate artery embolization (PAE) on male sexual function is currently the subject of debate in the literature. The main purpose of this study was to define changes in all domains of sexual activity after PAE, using the international index of erectile function score (IIEF-15). METHODS: A single-center retrospective study was conducted on 129 patients (mean age of 65.5 ± 7 years), who underwent PAE from February 2014 to January 2017 for symptomatic benign prostatic hyperplasia (BPH). Fifty consecutive patients fulfilling the inclusion criteria were evaluated before and after PAE follow-up using the IIEF-15, IPSS, prostate volume (PV) and cardiovascular risk factor and BPH drugs. The IIEF-15 domains analyzed were: erectile function (EF) ejaculation and orgasm (Ej/O), sexual desire (SD), intercourse satisfaction (IS) and overall satisfaction (OS). A paired sample t test or Wilcoxon signed-rank test was used to compare IIEF-15 between baseline and follow-up. RESULTS: The study showed nonsignificant change in IIEF-15 total score (58.0 ± 13.8 SD; p = 0.71) and the five domains (EF 24.5 ± 7.0 SD, p = 0.82; EJ/O 8.2 ± 2.3 SD, p = 0.50; SD 7.2 ± 2.7 SD, p = 0.57; IS 10.3 ± 3.0 SD, p = 0.77; OS 8.2 ± 2.7 SD; p = 0.11) after PAE. We also found a significant improvement in IPSS score after PAE. CONCLUSION: Based on the IIEF-15 questionnaire, PAE was showed to allow good urinary symptoms results and no deterioration in sexual function.
Entities:
Keywords:
International index of erectile function-15 (IIEF-15); International prostate symptom score (IPSS); Lower urinary tract symptoms (LUTS); Prostatic artery embolization (PAE); Sexual dysfunction; Symptomatic benign prostatic hyperplasia (BPH); Transurethral resection of the prostate (TURP)
Authors: Anak Agung Gde Oka; Gede Wirya Kusuma Duarsa; Putu Astri Novianti; Tjokorda Gde Bagus Mahadewa; Christopher Ryalino Journal: Res Rep Urol Date: 2019-04-10