Ana Márcia Menezes de Oliveira1, Elisama Gomes Magalhães de Melo1, Mário Luis Tavares Mendes2, Sheila Jaqueline Gomes Dos Santos Oliveira3, Carolina Santos Souza Tavares3, Andreia Centenaro Vaez4, Sara Juliana Abreu de Vasconcelos3, Hudson P Santos5, Victor Santana Santos6, Paulo Ricardo Saquete Martins-Filho7. 1. Postgraduate Program in Dentistry, Federal University of Sergipe, Aracaju, Brazil; Investigative Pathology Laboratory, Federal University of Sergipe, Sergipe, Brazil. 2. Investigative Pathology Laboratory, Federal University of Sergipe, Sergipe, Brazil. 3. Investigative Pathology Laboratory, Federal University of Sergipe, Sergipe, Brazil; Postgraduate Program in Health Sciences, Federal University of Sergipe, Sergipe, Brazil. 4. Investigative Pathology Laboratory, Federal University of Sergipe, Sergipe, Brazil; Postgraduate Program in Nursing, Federal University of Sergipe, Sergipe, Brazil. 5. School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. 6. Department of Nursing, Centre for Epidemiology and Public Health, Federal University of Alagoas, Arapiraca, Brazil. 7. Postgraduate Program in Dentistry, Federal University of Sergipe, Aracaju, Brazil; Investigative Pathology Laboratory, Federal University of Sergipe, Sergipe, Brazil; Postgraduate Program in Health Sciences, Federal University of Sergipe, Sergipe, Brazil. Electronic address: Martins-filho@ufs.br.
Abstract
OBJECTIVE: The aim of this study was to investigate oral and maxillofacial outcomes in children with congenital Zika syndrome (CZS) and the presence of nonnutritive sucking habits, functional habits, and features related to breastfeeding and nutrition of these children. STUDY DESIGN: We conducted a cross-sectional study with 45 children with CZS and 50 healthy controls in Sergipe state, Brazil, from February 2018 to June 2018. Demographic and clinical data, including breastfeeding and feeding data, were obtained for each child. Additionally, oral and maxillofacial evaluation was performed. RESULTS: Low weight (prevalence rate [PR] 8.33; 95% confidence interval [CI] 2.02-34.45), nonexclusive breastfeeding up to 6 months (PR 1.56; 95% CI 1.18-2.08); mouth breathing (PR 3.46; 95% CI 1.83-6.52); difficulty in swallowing (PR 6.00; 95% CI 2.53-14.25); and excessive salivation (PR 4.81; 95% CI 2.18-10.62) were more frequent in children with CZS. Children with CZS were more likely to have abnormal insertion of the upper labial frenulum (PR 7.04; 95% CI 2.23-22.20); ogival palate (PR 3.70; 95% CI 1.63-8.40), dental enamel defects (PR 2.22; 95% CI 1.05-4.69); and delayed dental eruption (PR 8.89; 95% CI 1.16-68.32) compared with healthy children. CONCLUSIONS: Children with CZS had a higher frequency of problems related to breastfeeding, low weight, and oral and maxillofacial abnormalities compared with healthy children.
OBJECTIVE: The aim of this study was to investigate oral and maxillofacial outcomes in children with congenital Zika syndrome (CZS) and the presence of nonnutritive sucking habits, functional habits, and features related to breastfeeding and nutrition of these children. STUDY DESIGN: We conducted a cross-sectional study with 45 children with CZS and 50 healthy controls in Sergipe state, Brazil, from February 2018 to June 2018. Demographic and clinical data, including breastfeeding and feeding data, were obtained for each child. Additionally, oral and maxillofacial evaluation was performed. RESULTS: Low weight (prevalence rate [PR] 8.33; 95% confidence interval [CI] 2.02-34.45), nonexclusive breastfeeding up to 6 months (PR 1.56; 95% CI 1.18-2.08); mouth breathing (PR 3.46; 95% CI 1.83-6.52); difficulty in swallowing (PR 6.00; 95% CI 2.53-14.25); and excessive salivation (PR 4.81; 95% CI 2.18-10.62) were more frequent in children with CZS. Children with CZS were more likely to have abnormal insertion of the upper labial frenulum (PR 7.04; 95% CI 2.23-22.20); ogival palate (PR 3.70; 95% CI 1.63-8.40), dental enamel defects (PR 2.22; 95% CI 1.05-4.69); and delayed dental eruption (PR 8.89; 95% CI 1.16-68.32) compared with healthy children. CONCLUSIONS:Children with CZS had a higher frequency of problems related to breastfeeding, low weight, and oral and maxillofacial abnormalities compared with healthy children.
Authors: Rita de Cássia Oliveira de Carvalho-Sauer; Maria da Conceição Nascimento Costa; Enny S Paixão; Natanael de Jesus Silva; Florisneide Rodrigues Barreto; Maria Gloria Teixeira Journal: BMC Pediatr Date: 2020-10-14 Impact factor: 2.125