Literature DB >> 32489874

Trichuriasis.

Arturo Carranza1, Karla Asturias1.   

Abstract

Entities:  

Keywords:  Clinical examination; Trichuris trichiura; Tropical disease

Year:  2020        PMID: 32489874      PMCID: PMC7256658          DOI: 10.1016/j.idcr.2020.e00821

Source DB:  PubMed          Journal:  IDCases        ISSN: 2214-2509


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A 16-year-old female presented with a 6-month history of dysentery associated with subjective fevers and weight loss of 10 kg. Her laboratory testing was remarkable for a hemoglobin of 9.1 g/dL, leukocytosis with neutrophilia (no eosinophilia), C-reactive protein > 15 mg/L, serum albumin of 2.5 g/dL and a negative HIV ELISA test. In the months prior to her presentation, she had two stool testing, which revealed positive fecal occult blood and the presence of Trichuris trichiura eggs, for which she was treated with nitazoxanide twice and metronidazole once. Due to persistent symptoms despite treatment, she was referred to our facility, to rule out ulcerative colitis. At the time of this presentation, physical examination showed poorly localized abdominal pain. A colonoscopy revealed diffuse parasitic infiltration of the colonic mucosa (Video, Appendix A). A biopsy was performed, showing histopathological findings of infectious colitis, evidence of adult parasitic colonic infiltration (Fig. 1, Panel A), and the presence of a gravid female parasite of Trichuris trichiura (Fig. 1, Panel B, arrow). The patient was treated symptomatically and mebendazole was started [1], [2].
Fig. 1

Histopathological findings compatible with adult parasitic colonic infiltration of Trichuris trichiura (Panel A), with evidence of a gravid female parasite (Panel B, arrow).

Histopathological findings compatible with adult parasitic colonic infiltration of Trichuris trichiura (Panel A), with evidence of a gravid female parasite (Panel B, arrow).

Authorship

Dr. Carranza and Dr. Asturias contributed equally in the clinical management of this patient and in writing the case presentation.

Prior presentations/publications

None.

Funding source

There is no funding source for this manuscript.

Author statement

Dr. Carranza and Dr. Asturias contributed equally in the clinical management of this patient and in writing, and reviewing, the case presentation.

Author contribution

All authors contributed equally to the clinical management of the patient and to the writing of this report.

Declaration of Competing Interest

We declare no conflict of interest.
  2 in total

Review 1.  Soil-transmitted helminth infections.

Authors:  Peter Mark Jourdan; Poppy H L Lamberton; Alan Fenwick; David G Addiss
Journal:  Lancet       Date:  2017-09-04       Impact factor: 79.321

2.  Efficacy and Safety of a Single-Dose Mebendazole 500 mg Chewable, Rapidly-Disintegrating Tablet for Ascaris lumbricoides and Trichuris trichiura Infection Treatment in Pediatric Patients: A Double-Blind, Randomized, Placebo-Controlled, Phase 3 Study.

Authors:  Steven A Silber; Ermias Diro; Netsanet Workneh; Zeleke Mekonnen; Bruno Levecke; Peter Steinmann; Irenee Umulisa; Hailemaryam Alemu; Benny Baeten; Marc Engelen; Peter Hu; Andrew Friedman; Alan Baseman; Joseph Mrus
Journal:  Am J Trop Med Hyg       Date:  2017-08-31       Impact factor: 2.345

  2 in total

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