Fiona Barnes1, Lynda Graham1, Prakash Loganathan2,3, Vrinda Nair4,5. 1. Neonatal Intensive Care Unit, University Hospital, Crosshouse, Kilmarnock, Ayrshire, KA2 0BE, UK. 2. Neonatal Intensive Care Unit, James Cook University Hospital, Marton road, Middlesbrough, TS4 3BW, UK. 3. Clinical Academic Office, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK. 4. Neonatal Intensive Care Unit, James Cook University Hospital, Marton road, Middlesbrough, TS4 3BW, UK. vrinda.nair1@nhs.net. 5. Clinical Academic Office, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK. vrinda.nair1@nhs.net.
Abstract
OBJECTIVE: To assess the value of general movements (GMs) in predicting the neurodevelopmental outcome using Bayley Scale of Infant Development III (BSID-III) at two years of age in very low birth weight (VLBW) infants. METHODS: This is a five-year observational study (January 2012-June 2017). Two hundred twenty-seven VLBW infants were assessed in the neurodevelopmental clinic between Jan 2012 and June 2017. Of these 137 infants had GMs assessments at 3 mo post term (first visit to the clinic). RESULTS: Absence of fidgety movements (FMs) at 3 mo post term had high specificity and negative predictive value for moderate to severe neurodevelopmental outcome in motor, cognition and language domains (composite score less than 70 in the Bayley III scales of Infant development scores). At 3 mo post term, absent FMs had high sensitivity, specificity and negative predictive value (NPV) for cerebral palsy (CP). CONCLUSIONS: GMs assessment at 3 mo post term could be considered as an important screening tool for early identification of VLBW infants who are at risk of neurodevelopmental impairment/cerebral palsy.
OBJECTIVE: To assess the value of general movements (GMs) in predicting the neurodevelopmental outcome using Bayley Scale of Infant Development III (BSID-III) at two years of age in very low birth weight (VLBW) infants. METHODS: This is a five-year observational study (January 2012-June 2017). Two hundred twenty-seven VLBW infants were assessed in the neurodevelopmental clinic between Jan 2012 and June 2017. Of these 137 infants had GMs assessments at 3 mo post term (first visit to the clinic). RESULTS: Absence of fidgety movements (FMs) at 3 mo post term had high specificity and negative predictive value for moderate to severe neurodevelopmental outcome in motor, cognition and language domains (composite score less than 70 in the Bayley III scales of Infant development scores). At 3 mo post term, absent FMs had high sensitivity, specificity and negative predictive value (NPV) for cerebral palsy (CP). CONCLUSIONS:GMs assessment at 3 mo post term could be considered as an important screening tool for early identification of VLBW infants who are at risk of neurodevelopmental impairment/cerebral palsy.
Entities:
Keywords:
Cerebral palsy; General movements; Neurodevelopment
Authors: Loïs C Span; Nienke H van Dokkum; Anne-Greet Ravensbergen; Arend F Bos; Artur C Jaschke Journal: Int J Environ Res Public Health Date: 2021-06-18 Impact factor: 3.390