| Literature DB >> 32488788 |
N G Plekhova1, I N Lyapun2, E I Drobot2, D V Shevchuk3, S L Sinebryukhov4, D V Mashtalyar4, S V Gnedenkov4.
Abstract
Bioactive coatings on implants affect osteogenic differentiation of mesenchymal stem cells (MSC). We studied the morphofunctional state of bone marrow MSC cultured on the surface of calcium phosphate coatings on titanium formed by plasma electrolytic oxidation (PEO). The biocompatible properties of the coatings manifested in the absence of the cytotoxic effect on cells. High expression of receptors (CD90, CD29, and CD106), enhanced synthesis of osteocalcin and osteopontin, and changes in surface architectonics of MSC adherent to the samples confirmed osteoinductive properties of the calcium phosphate PEO coating.Entities:
Keywords: cell technologies; coatings; mesenchymal stem cells; titanium implants
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Year: 2020 PMID： 32488788 DOI： 10.1007/s10517-020-04841-6
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804