Literature DB >> 32488025

Bound Together: How Psychoanalysis Diminishes Inter-generational DNA Trauma.

Roberto Colangeli1.   

Abstract

The concept of intergenerational transmission of trauma plays a fundamental role in psychoanalysis. While it is known that intergenerational trauma can be transmitted through attachment relationships, a new branch of genetics (epigenetics) has emerged to study the interaction between human behavior and changes in DNA expression. Therefore, psychoanalysis, which has proven to reduce the intergenerational transmission of trauma from a behavioral perspective, can play a positive role in regulating DNA changes caused by environmental stress. The present paper focuses on recent research suggesting a direct correlation between psychological trauma and DNA modifications. In particular, DNA changes caused by psychological trauma can be transmitted from generation to generation, validating the psychoanalytic concept of intergenerational transmission of trauma. This evidence not only supports the essential role psychoanalysis has in influencing human behavior, but also suggests that it affects not only the individuals who undergo it but their offspring, as well, via the epigenetic passage of DNA.

Entities:  

Keywords:  DNA; brain research; epigenetics; intergenerational transmission of trauma; psychoanalysis; trauma

Mesh:

Substances:

Year:  2020        PMID: 32488025     DOI: 10.1057/s11231-020-09247-x

Source DB:  PubMed          Journal:  Am J Psychoanal        ISSN: 0002-9548


  82 in total

1.  Transgenerational sex-specific impact of preconception stress on the development of dendritic spines and dendritic length in the medial prefrontal cortex.

Authors:  Joerg Bock; Julia Poeschel; Julia Schindler; Florian Börner; Alice Shachar-Dadon; Neta Ferdman; Inna Gaisler-Salomon; Micah Leshem; Katharina Braun; Gerd Poeggel
Journal:  Brain Struct Funct       Date:  2014-11-14       Impact factor: 3.270

Review 2.  Intergenerational Transmission of Stress in Humans.

Authors:  Mallory E Bowers; Rachel Yehuda
Journal:  Neuropsychopharmacology       Date:  2015-08-17       Impact factor: 7.853

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Review 4.  The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders.

Authors:  Elisabeth B Binder
Journal:  Psychoneuroendocrinology       Date:  2009-12       Impact factor: 4.905

Review 5.  The development of a Clinician-Administered PTSD Scale.

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Journal:  J Trauma Stress       Date:  1995-01

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Journal:  Nature       Date:  1967-01-14       Impact factor: 49.962

7.  Genome-wide DNA methylation investigation of glucocorticoid exposure within buccal samples.

Authors:  Patricia R Braun; Mai Tanaka-Sahker; Aubrey C Chan; Sydney S Jellison; Mason J Klisares; Benjamin W Hing; Yaseen Shabbir; Lindsey N Gaul; Yasunori Nagahama; Julian Robles; Jonathan T Heinzman; Sayeh Sabbagh; Ellyn M Cramer; Gabrielle N Duncan; Kumi Yuki; Liesl N Close; Brian J Dlouhy; Matthew A Howard; Hiroto Kawasaki; Kyle M Stein; James B Potash; Gen Shinozaki
Journal:  Psychiatry Clin Neurosci       Date:  2019-03-28       Impact factor: 5.188

8.  Pathological brain plasticity and cognition in the offspring of males subjected to postnatal traumatic stress.

Authors:  J Bohacek; M Farinelli; O Mirante; G Steiner; K Gapp; G Coiret; M Ebeling; G Durán-Pacheco; A L Iniguez; F Manuella; J-L Moreau; I M Mansuy
Journal:  Mol Psychiatry       Date:  2014-08-05       Impact factor: 15.992

9.  The infantile psychic trauma from us to Freud: pure trauma, retroactivity and reconstruction.

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Journal:  Int J Psychoanal       Date:  1988

10.  Methylation of FKBP5 and SLC6A4 in Relation to Treatment Response to Mindfulness Based Stress Reduction for Posttraumatic Stress Disorder.

Authors:  Jeffrey R Bishop; Adam M Lee; Lauren J Mills; Paul D Thuras; Seenae Eum; Doris Clancy; Christopher R Erbes; Melissa A Polusny; Gregory J Lamberty; Kelvin O Lim
Journal:  Front Psychiatry       Date:  2018-09-18       Impact factor: 4.157

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