Literature DB >> 32487691

Before Watson and Crick in 1953 Came Friedrich Miescher in 1869.

Ehud Lamm1, Oren Harman2, Sophie Juliane Veigl3.   

Abstract

In 1869, the young Swiss biochemist Friedrich Miescher discovered the molecule we now refer to as DNA, developing techniques for its extraction. In this paper we explain why his name is all but forgotten, and his role in the history of genetics is mostly overlooked. We focus on the role of national rivalries and disciplinary turf wars in shaping historical memory, and on how the story we tell shapes our understanding of the science. We highlight that Miescher could just as correctly be portrayed as the person who understood the chemical nature of chromatin (before the term existed), and the first to suggest how stereochemistry might serve as the basis for the transmission of hereditary variation.
Copyright © 2020 by the Genetics Society of America.

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Year:  2020        PMID: 32487691      PMCID: PMC7268995          DOI: 10.1534/genetics.120.303195

Source DB:  PubMed          Journal:  Genetics        ISSN: 0016-6731            Impact factor:   4.562


  10 in total

1.  Code unknown: histories of the gene. [Reviews of: Keller, EF. The century of the gene. Harvard University Press, 2000 and Kay, LE. Who wrote the book of life? A history of the genetic code. Stanford University Press, 2000].

Authors:  C Waldby
Journal:  Soc Stud Sci       Date:  2001-10       Impact factor: 3.885

2.  1953 and all that: a tale of two sciences.

Authors:  P Kitcher
Journal:  Philos Rev       Date:  1984

3.  Who wrote the book of life? Information and the transformation of molecular biology, 1945-55.

Authors:  L E Kay
Journal:  Sci Context       Date:  1995       Impact factor: 0.425

Review 4.  Friedrich Miescher and the discovery of DNA.

Authors:  Ralf Dahm
Journal:  Dev Biol       Date:  2005-02-15       Impact factor: 3.582

Review 5.  Discovering DNA: Friedrich Miescher and the early years of nucleic acid research.

Authors:  Ralf Dahm
Journal:  Hum Genet       Date:  2007-09-28       Impact factor: 4.132

6.  Not just "a clever way to detect whether DNA really made RNA": The invention of DNA-RNA hybridization and its outcome.

Authors:  Susie Fisher
Journal:  Stud Hist Philos Biol Biomed Sci       Date:  2015-07-25

7.  The discovery of DNA.

Authors:  A E Mirsky
Journal:  Sci Am       Date:  1968-06       Impact factor: 2.142

8.  Friedrich Miescher's Discovery in the Historiography of Genetics: From Contamination to Confusion, from Nuclein to DNA.

Authors:  Sophie Juliane Veigl; Oren Harman; Ehud Lamm
Journal:  J Hist Biol       Date:  2020-06-10       Impact factor: 1.326

9.  Cell chemistry in Miescher's day.

Authors:  R Olby
Journal:  Med Hist       Date:  1969-10       Impact factor: 1.419

Review 10.  On the Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life.

Authors: 
Journal:  Br Foreign Med Chir Rev       Date:  1860-04
  10 in total

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