Literature DB >> 32483985

Medicinal chemistry strategies of targeting HIV-1 capsid protein for antiviral treatment.

Shujing Xu1, Lin Sun1, Boshi Huang2, Xinyong Liu1, Peng Zhan1.   

Abstract

Entities:  

Keywords:  CA inhibitor; drug design; medicinal chemistry strategy

Mesh：

Substances：

Year:  2020        PMID： 32483985     DOI： 10.4155/fmc-2020-0084

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  4 in total

1.  Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.

Authors:  Shujing Xu; Lin Sun; Alexej Dick; Waleed A Zalloum; Tianguang Huang; Megan E Meuser; Xujie Zhang; Yucen Tao; Srinivasulu Cherukupalli; Dang Ding; Xiao Ding; Shenghua Gao; Xiangyi Jiang; Dongwei Kang; Erik De Clercq; Christophe Pannecouque; Simon Cocklin; Xinyong Liu; Peng Zhan
Journal:  Eur J Med Chem       Date:  2021-10-09       Impact factor: 7.088

2.  Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitors.

Authors:  Jing Li; Xiangyi Jiang; Alexej Dick; Prem Prakash Sharma; Chin-Ho Chen; Brijesh Rathi; Dongwei Kang; Zhao Wang; Xiangkai Ji; Kuo-Hsiung Lee; Simon Cocklin; Xinyong Liu; Peng Zhan
Journal:  Bioorg Med Chem       Date:  2021-09-17       Impact factor: 3.461

Review 3.  Newly Emerging Strategies in Antiviral Drug Discovery: Dedicated to Prof. Dr. Erik De Clercq on Occasion of His 80th Anniversary.

Authors:  Shujing Xu; Dang Ding; Xujie Zhang; Lin Sun; Dongwei Kang; Boshi Huang; Xinyong Liu; Peng Zhan
Journal:  Molecules       Date:  2022-01-27       Impact factor: 4.411

4.  Metabolite Identification of HIV-1 Capsid Modulators PF74 and 11L in Human Liver Microsomes.

Authors:  Shujing Xu; Lin Sun; Dang Ding; Xujie Zhang; Xinyong Liu; Peng Zhan
Journal:  Metabolites       Date:  2022-08-16
  4 in total

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