Literature DB >> 32479211

Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice.

Samira Reyhani1, Bahareh Abbaspanah2, Seyed Hadi Mousavi3.   

Abstract

Mesenchymal stem cells (MSCs) have provided a promising tool for cell therapy. Umbilical cord (UC) is one of the best sources of MSCs since its collection is noninvasive, and effortless, and the cells from this source are more capable and prolific. It has been proven that the differentiation, migration and protective properties of UC-MSCs are superior compared with other kinds of stem cells. Moreover, incurable neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis, Parkinson's disease and Huntington, encourage scientists to apply UC-MSCs transplantation in order to find a definite treatment. This review will focus on the preclinical and clinical use of mesenchymal stem cells derived from human umbilical cord in the treatment of neurodegenerative disorders.

Entities:  

Keywords:  Alzheimer’s disease; Huntington disease; Parkinson’s disease; amyotrophic lateral sclerosis; cerebral palsy; multiple sclerosis; neurodegenerative disease; spinal cord injury; stem cell therapies; umbilical cord mesenchymal stem cells

Mesh：

Year:  2020        PMID： 32479211     DOI： 10.2217/rme-2019-0119

Source DB:  PubMed          Journal:  Regen Med        ISSN： 1746-0751            Impact factor:   3.806


  8 in total

Review 1.  Stem cell-based therapy for human diseases.

Authors:  Duc M Hoang; Phuong T Pham; Trung Q Bach; Anh T L Ngo; Quyen T Nguyen; Trang T K Phan; Giang H Nguyen; Phuong T T Le; Van T Hoang; Nicholas R Forsyth; Michael Heke; Liem Thanh Nguyen
Journal:  Signal Transduct Target Ther       Date:  2022-08-06

2.  Reproductive and Developmental Toxicity Assessment of Human Umbilical Cord Mesenchymal Stem Cells in Rats.

Authors:  Xiaobo Li; Qijing Huang; Xiangxiang Zhang; Changfeng Xie; Muyun Liu; Yueming Yuan; Jianjia Feng; Haoyu Xing; Li Ru; Zheng Yuan; Zhiyong Xu; YaoXiang Yang; Yan Long; Chengfeng Xing; Jianping Song; Xiang Hu; Qin Xu
Journal:  Front Cell Dev Biol       Date:  2022-05-19

3.  MiR-455-5p upregulation in umbilical cord mesenchymal stem cells attenuates endometrial injury and promotes repair of damaged endometrium via Janus kinase/signal transducer and activator of transcription 3 signaling.

Authors:  Dongyan Sun; Zhihe Jiang; Yanling Chen; Di Shang; Pan Miao; Jian Gao
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

4.  In Vitro Neuroprotective Effect of the Bovine Umbilical Vein Endothelial Cell Conditioned Medium Mediated by Downregulation of IL-1β, Caspase-3, and Caspase-9 Expression.

Authors:  Vinny A Larasati; Gregorius V Lembang; Yudy Tjahjono; Sugi Winarsih; Ika Dewi Ana; Hevi Wihadmadyatami; Dwi L Kusindarta
Journal:  Vet Sci       Date:  2022-01-27

Review 5.  Human umbilical cord blood mononuclear cells transplantation for perinatal brain injury.

Authors:  Yufeng Xi; Guang Yue; Shuqiang Gao; Rong Ju; Yujia Wang
Journal:  Stem Cell Res Ther       Date:  2022-09-05       Impact factor: 8.079

Review 6.  The optimal transplantation strategy of umbilical cord mesenchymal stem cells in spinal cord injury: a systematic review and network meta-analysis based on animal studies.

Authors:  Yubao Lu; Wei Zhang; Zhenming Tian; Qian Liang; Chenrui Liu; Yingjie Wu; Liangming Zhang; Limin Rong
Journal:  Stem Cell Res Ther       Date:  2022-09-02       Impact factor: 8.079

7.  The Neural Multilineage Differentiation Capacity of Human Neural Precursors from the Umbilical Cord-Ready to Bench for Clinical Trials.

Authors:  Daiany de Souza Dobuchak; Priscila Elias Ferreira Stricker; Nathalia Barth de Oliveira; Bassam Felipe Mogharbel; Nádia Nascimento da Rosa; Dilcele Silva Moreira Dziedzic; Ana Carolina Irioda; Katherine Athayde Teixeira de Carvalho
Journal:  Membranes (Basel)       Date:  2022-09-09

8.  An optimized method for obtaining clinical-grade specific cell subpopulations from human umbilical cord-derived mesenchymal stem cells.

Authors:  Yali Jia; Ailin Wang; Bichun Zhao; Chao Wang; Ruyu Su; Biao Zhang; Zeng Fan; Quan Zeng; Lijuan He; Xuetao Pei; Wen Yue
Journal:  Cell Prolif       Date:  2022-06-29       Impact factor: 8.755
  8 in total

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