Literature DB >> 32477848

An assessment of potential nutritive and medicinal properties of Mucuna pruriens: a natural food legume.

Ruhi Pathania1, Prince Chawla2, Huma Khan1, Ravinder Kaushik3, Mohammed Azhar Khan1.   

Abstract

Mucuna pruriens belongs to the Fabaceae family and is ordinarily known as velvet bean, in English cowitch and Hindi Kawaanch. The restorative quality of this bean makes it an excellent component in pharmaceutical and therapeutic applications. Apart from high protein and starch content, these beans contain (l-Dopa) 3, 4-dihydroxy-l-phenylalanine, which exhibits several medicinal properties. However, it is poisonous when ingested by ruminants. The obstruction to the advancement of Mucuna as nutrition or food is the nearness of antinutrients, which are high as opposed to other uncommon vegetables. Also, this legume is considered as a future restorative herb because of its anticholesterolemic, anti-Parkinson, antioxidant, antidiabetic, sexual enhancing, anti-inflammatory, antimicrobial, and antivenom activities. It also exhibits anticancer activities, but very few studies have been done. The seeds of Mucuna pruriens also contain a vast range of phytochemical constituents such as alkaloids, glycosides, saponins, reducing sugars, and tannins, which provide an avenue to explore it for wider applications. This review sheds light on the possible mechanism of action of Mucuna pruriens on some diseases (hypoglycemia, Parkinson's disease, microbial diseases and tumor). and also fills the gap in the studies of Mucuna pruriens. and Further more in vitro and in vivo studies should be done to explore the potential of these seeds against many diseases, its application as a food source, its antinutrient, and harmful properties as well as its nutraceutical perspective. © King Abdulaziz City for Science and Technology 2020.

Entities:  

Keywords:  Antioxidant; Mucuna pruriens; Nutraceutical; Parkinson’s ailment; Phytochemicals; l-Dopa

Year:  2020        PMID: 32477848      PMCID: PMC7239958          DOI: 10.1007/s13205-020-02253-x

Source DB:  PubMed          Journal:  3 Biotech        ISSN: 2190-5738            Impact factor:   2.406


  41 in total

1.  Proteomic analysis of the pathophysiological process involved in the antisnake venom effect of Mucuna pruriens extract.

Authors:  Roberto Guerranti; Ifeanyi G Ogueli; Erica Bertocci; Chiara Muzzi; John C Aguiyi; Riccardo Cianti; Alessandro Armini; Luca Bini; Roberto Leoncini; Enrico Marinello; Roberto Pagani
Journal:  Proteomics       Date:  2008-01       Impact factor: 3.984

2.  Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract.

Authors:  Stephen O Majekodunmi; Ademola A Oyagbemi; Solomon Umukoro; Oluwatoyin A Odeku
Journal:  Asian Pac J Trop Med       Date:  2011-08       Impact factor: 1.226

3.  Extraction of bioactive principles from Mucuna pruriens seeds.

Authors:  Laxminarain Misra; Hildebert Wagner
Journal:  Indian J Biochem Biophys       Date:  2007-02       Impact factor: 1.918

4.  Protective effects of Mucuna pruriens seed extract pretreatment against cardiovascular and respiratory depressant effects of Calloselasma rhodostoma (Malayan pit viper) venom in rats.

Authors:  S Y Fung; N H Tan; S M Sim
Journal:  Trop Biomed       Date:  2010-12       Impact factor: 0.623

5.  Effect of the alcohol extract of the seeds of Mucuna pruriens on free radicals and oxidative stress in albino rats.

Authors:  Yamini B Tripathi; Anil K Upadhyay
Journal:  Phytother Res       Date:  2002-09       Impact factor: 5.878

6.  Hypoglycemic effect of Mucuna pruriens seed extract on normal and streptozotocin-diabetic rats.

Authors:  Anusha Bhaskar; V G Vidhya; M Ramya
Journal:  Fitoterapia       Date:  2008-07-10       Impact factor: 2.882

7.  Alkaloidal constituents of Mucuna pruriens seeds.

Authors:  Laxminarain Misra; Hildebert Wagner
Journal:  Phytochemistry       Date:  2004-09       Impact factor: 4.072

8.  The protective effect of Mucuna pruriens seeds against snake venom poisoning.

Authors:  Nget Hong Tan; Shin Yee Fung; Si Mui Sim; Enrico Marinello; Roberto Guerranti; John C Aguiyi
Journal:  J Ethnopharmacol       Date:  2009-03-26       Impact factor: 4.360

9.  Effects of soybean ingestion on pharmacokinetics of levodopa and motor symptoms of Parkinson's disease--In relation to the effects of Mucuna pruriens.

Authors:  Yasuhiro Nagashima; Tomoyoshi Kondo; Mayumi Sakata; Jinsoo Koh; Hidefumi Ito
Journal:  J Neurol Sci       Date:  2016-01-06       Impact factor: 3.181

10.  Levodopa-Reduced Mucuna pruriens Seed Extract Shows Neuroprotective Effects against Parkinson's Disease in Murine Microglia and Human Neuroblastoma Cells, Caenorhabditis elegans, and Drosophila melanogaster.

Authors:  Shelby L Johnson; Hyun Y Park; Nicholas A DaSilva; Dhiraj A Vattem; Hang Ma; Navindra P Seeram
Journal:  Nutrients       Date:  2018-08-22       Impact factor: 5.717

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  3 in total

1.  Development of Jelly Loaded with Nanogel Containing Natural L-Dopa from Mucuna pruriens Seed Extract for Neuroprotection in Parkinson's Disease.

Authors:  Chuda Chittasupho; Sarin Tadtong; Suwanna Vorarat; Witcha Imaram; Sirivan Athikomkulchai; Weerasak Samee; Vipaporn Sareedenchai; Thanu Thongnopkoon; Siriporn Okonogi; Narisa Kamkaen
Journal:  Pharmaceutics       Date:  2022-05-17       Impact factor: 6.525

Review 2.  Mucuna pruriens in Parkinson's and in some other diseases: recent advancement and future prospective.

Authors:  Sachchida Nand Rai; Vivek K Chaturvedi; Payal Singh; Brijesh Kumar Singh; M P Singh
Journal:  3 Biotech       Date:  2020-11-10       Impact factor: 2.406

3.  Therapeutic potential of Mucuna pruriens (Linn.) on high-fat diet-induced testicular and sperm damage in rats.

Authors:  Anuradha Murugesan; Karthik Ganesh Mohanraj; Khayinmi Wungpam Shimray; Mohammad Zafar Iqbal Khan; Prakash Seppan
Journal:  Avicenna J Phytomed       Date:  2022 Sep-Oct
  3 in total

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