Literature DB >> 32477663

Mapping Local Biospecimen Records to the OMOP Common Data Model.

Chelsea L Michael1,2, Evan T Sholle3, Regina T Wulff4, Gail J Roboz4, Thomas R Campion2,3,5,6.   

Abstract

Research to support precision medicine for leukemia patients requires integration of biospecimen and clinical data. The Observational Medical Outcomes Partnership common data model (OMOP CDM) and its Specimen table presents a potential solution. Although researchers have described progress and challenges in mapping electronic health record (EHR) data to populate the OMOP CDM, to our knowledge no studies have described populating the OMOP CDM with biospecimen data. Using biobank data from our institution, we mapped 26% of biospecimen records to the OMOP Specimen table. Records failed mapping due to local codes for time point that were incompatible with the OMOP reference terminology. We recommend expanding allowable codes to encompass research data, adding foreign keys to leverage additional OMOP tables with data from other sources or to store additional specimen details, and considering a new table to represent processed samples and inventory. ©2020 AMIA - All rights reserved.

Entities:  

Year:  2020        PMID: 32477663      PMCID: PMC7233045     

Source DB:  PubMed          Journal:  AMIA Jt Summits Transl Sci Proc


  2 in total

Review 1.  Artificial Intelligence, Healthcare, Clinical Genomics, and Pharmacogenomics Approaches in Precision Medicine.

Authors:  Habiba Abdelhalim; Asude Berber; Mudassir Lodi; Rihi Jain; Achuth Nair; Anirudh Pappu; Kush Patel; Vignesh Venkat; Cynthia Venkatesan; Raghu Wable; Matthew Dinatale; Allyson Fu; Vikram Iyer; Ishan Kalove; Marc Kleyman; Joseph Koutsoutis; David Menna; Mayank Paliwal; Nishi Patel; Thirth Patel; Zara Rafique; Rothela Samadi; Roshan Varadhan; Shreyas Bolla; Sreya Vadapalli; Zeeshan Ahmed
Journal:  Front Genet       Date:  2022-07-06       Impact factor: 4.772

2.  Extract, transform, load framework for the conversion of health databases to OMOP.

Authors:  Juan C Quiroz; Tim Chard; Zhisheng Sa; Angus Ritchie; Louisa Jorm; Blanca Gallego
Journal:  PLoS One       Date:  2022-04-11       Impact factor: 3.240

  2 in total

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