Literature DB >> 32476779

The 'apple core' cement spacer for the management of massive bone loss in two-stage revision knee arthroplasty for infection.

Nima Razii1,2, Rahul Kakar1,3, Rhidian Morgan-Jones1.   

Abstract

Antibiotic-loaded cement spacers are used in two-stage revision knee arthroplasty for infection, but commercially available spacers may not always be suitable for significant bone loss or soft tissue failure in multiply revised cases. We describe a technique for producing an on-table, static, reinforced cement spacer - the 'apple core' spacer - with the intended outcome of providing joint stability in such patients, prior to undertaking a second-stage procedure. Following a radical debridement, the spacer is made of three components: (1) a 'central bar' of external fixator connecting rods, combined using cerclage wires as needed; (2) a standard polymethylmethacrylate cement 'apple core'; and (3) a covering 'skin' of high dose antibiotic-loaded cement, which is stippled as it sets, to increase the surface area and facilitate antibiotic elution. This technique was performed in nine patients who underwent two-stage salvage revision for complex, recurrent infected total knee arthroplasty at a single institution. All patients successfully went on to definitive second-stage reimplantation and have retained their limbs. The 'apple core' cement spacer allows massive bone defects to be effectively managed between staged revision procedures.
© 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Bone loss; Cement spacer; Knee arthroplasty; Limb salvage; Periprosthetic infection; Revision

Year:  2020        PMID: 32476779      PMCID: PMC7248581          DOI: 10.1016/j.jor.2020.05.011

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  21 in total

Review 1.  The management of an infected total knee arthroplasty.

Authors:  T Gehrke; P Alijanipour; J Parvizi
Journal:  Bone Joint J       Date:  2015-10       Impact factor: 5.082

2.  The epidemiology of revision total knee and hip arthroplasty in England and Wales: a comparative analysis with projections for the United States. A study using the National Joint Registry dataset.

Authors:  A Patel; G Pavlou; R E Mújica-Mota; A D Toms
Journal:  Bone Joint J       Date:  2015-08       Impact factor: 5.082

3.  In vitro study of the efficacy of acrylic bone cement loaded with supplementary amounts of gentamicin: effect on mechanical properties, antibiotic release, and biofilm formation.

Authors:  Nicholas Dunne; Janet Hill; Patricia McAfee; Katy Todd; Rachel Kirkpatrick; Michael Tunney; Sheila Patrick
Journal:  Acta Orthop       Date:  2007-12       Impact factor: 3.717

Review 4.  Classification and preoperative radiographic evaluation: knee.

Authors:  G A Engh; D J Ammeen
Journal:  Orthop Clin North Am       Date:  1998-04       Impact factor: 2.472

5.  Local bio-absorbable antibiotic delivery in calcium sulfate beads in hip and knee arthroplasty.

Authors:  Zachary C Lum; Gavin C Pereira
Journal:  J Orthop       Date:  2018-05-07

6.  Two stage revision knee arthroplasty for infection with massive bone loss. A technique to achieve spacer stability.

Authors:  R S J Nickinson; T N Board; A K Gambhir; M L Porter; P R Kay
Journal:  Knee       Date:  2011-01-06       Impact factor: 2.199

7.  Comparison of the elution properties of commercially available gentamicin and bone cement containing vancomycin with 'home-made' preparations.

Authors:  N M Frew; T Cannon; T Nichol; T J Smith; I Stockley
Journal:  Bone Joint J       Date:  2017-01       Impact factor: 5.082

8.  Primary cement spacers: a cost-effective, durable limb salvage option for knee tumors.

Authors:  Ajay Puri; Ashish Gulia; Manish Pruthi; S Koushik
Journal:  Knee       Date:  2011-07-19       Impact factor: 2.199

9.  Effect of varying surface patterns on antibiotic elution from antibiotic-loaded bone cement.

Authors:  B A Masri; C P Duncan; C P Beauchamp; N J Paris; J Arntorp
Journal:  J Arthroplasty       Date:  1995-08       Impact factor: 4.757

10.  Two-stage reimplantation for the salvage of infected total knee arthroplasty.

Authors:  J N Insall; F M Thompson; B D Brause
Journal:  J Bone Joint Surg Am       Date:  1983-10       Impact factor: 5.284

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