Literature DB >> 32476535

Soft drugs: design principles, success stories, and future perspectives.

Peter Buchwald1.   

Abstract

Keywords:  Antedrug; drug metabolism; esterases; methylphenidate; prodrug; sofpironium; therapeutic index; toxic metabolite

Mesh：

Substances：

Year:  2020        PMID： 32476535     DOI： 10.1080/17425255.2020.1777280

Source DB:  PubMed          Journal:  Expert Opin Drug Metab Toxicol        ISSN： 1742-5255            Impact factor:   4.481


× No keyword cloud information.
  4 in total

Review 1.  Structural Modification in Anesthetic Drug Development for Prodrugs and Soft Drugs.

Authors:  Chaoyi Deng; Jin Liu; Wensheng Zhang
Journal:  Front Pharmacol       Date:  2022-07-01       Impact factor: 5.988

2.  Comparative chemical and biological hydrolytic stability of homologous esters and isosteres.

Authors:  Hygor M R de Souza; Jéssica S Guedes; Rosana H C N Freitas; Luis G V Gelves; Harold H Fokoue; Carlos Mauricio R Sant'Anna; Eliezer J Barreiro; Lidia M Lima
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.051

3.  Distribution- and Metabolism-Based Drug Discovery: A Potassium-Competitive Acid Blocker as a Proof of Concept.

Authors:  Ming-Shu Wang; Yi Gong; Lin-Sheng Zhuo; Xing-Xing Shi; Yan-Guang Tian; Chang-Kang Huang; Wei Huang; Guang-Fu Yang
Journal:  Research (Wash D C)       Date:  2022-07-22

Review 4.  TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy.

Authors:  Asia Fernández-Carvajal; Gregorio Fernández-Ballester; Antonio Ferrer-Montiel
Journal:  Front Mol Neurosci       Date:  2022-09-02       Impact factor: 6.261
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.