Saliu Balogun1, David Scott2, Flavia Cicuttini3, Graeme Jones4, Dawn Aitken4. 1. Menzies Institute for Medical Research, University of Tasmania, Australia; National Center for Epidemiology and Population Health, Australian National University, Canberra, University of Tasmania, Australia. Electronic address: Saliu.Balogun@utas.edu.au. 2. Department of Medicine, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, 3168, Australia; Melbourne Medical School (Western Campus) and Australian Institute for Musculoskeletal Science, The University of Melbourne and Western Health, St Albans, Victoria, 3021, Australia. 3. Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. 4. Menzies Institute for Medical Research, University of Tasmania, Australia.
Abstract
AIMS: To describe the associations between interindividual (between-person) and intraindividual (within-person) variability in physical activity (PA) and knee pain and functional limitation among older adults. We also investigated the potential bidirectional association of between-person and within-person variability in knee pain and functional limitation with PA. METHOD: Participants (N = 1064; 51% women; mean age 63 ± 7.4 years) were measured at baseline, 2.5, and 5 years. PA was measured using pedometers. Knee pain and functional limitation were assessed using the WOMAC scale. A two-part hurdle model, with adjustment for confounders, estimated the association of between-person and within-person variability in PA with knee pain/functional limitation (as the outcome). Linear mixed effect regression models described the association of between-person and within-person variability in knee pain and functional limitation with PA (as the outcome). RESULTS: Between-person effects showed that participants with a higher 5-year average PA had lower average WOMAC scores (β= -1.17, 95% CI: -1.82, -0.51). Within-person effects showed that at time-points when participants had a higher PA level than average, they also had lower WOMAC scores (β= -0.85, 95% CI: -1.36, -0.35). Conversely, both between-person (β= -15.6, 95% CI: -22.5, -8.8) and within-person increase (β= -7.4, 95% CI: -13.5, -1.4) in WOMAC scores were associated with lower PA. CONCLUSION: These findings suggest that PA and knee pain/dysfunctional contribute to the development of one another. Pain can lead to changes in inter- and intraindividual PA levels, but the reverse is also possible - changes in PA results in changes in inter- and intraindividual pain/dysfunctional levels.
AIMS: To describe the associations between interindividual (between-person) and intraindividual (within-person) variability in physical activity (PA) and knee pain and functional limitation among older adults. We also investigated the potential bidirectional association of between-person and within-person variability in knee pain and functional limitation with PA. METHOD:Participants (N = 1064; 51% women; mean age 63 ± 7.4 years) were measured at baseline, 2.5, and 5 years. PA was measured using pedometers. Knee pain and functional limitation were assessed using the WOMAC scale. A two-part hurdle model, with adjustment for confounders, estimated the association of between-person and within-person variability in PA with knee pain/functional limitation (as the outcome). Linear mixed effect regression models described the association of between-person and within-person variability in knee pain and functional limitation with PA (as the outcome). RESULTS: Between-person effects showed that participants with a higher 5-year average PA had lower average WOMAC scores (β= -1.17, 95% CI: -1.82, -0.51). Within-person effects showed that at time-points when participants had a higher PA level than average, they also had lower WOMAC scores (β= -0.85, 95% CI: -1.36, -0.35). Conversely, both between-person (β= -15.6, 95% CI: -22.5, -8.8) and within-person increase (β= -7.4, 95% CI: -13.5, -1.4) in WOMAC scores were associated with lower PA. CONCLUSION: These findings suggest that PA and knee pain/dysfunctional contribute to the development of one another. Pain can lead to changes in inter- and intraindividual PA levels, but the reverse is also possible - changes in PA results in changes in inter- and intraindividual pain/dysfunctional levels.
Authors: Sofía López-Roig; Carmen Ecija; Cecilia Peñacoba; Sofía Ivorra; Ainara Nardi-Rodríguez; Oscar Lecuona; María Angeles Pastor-Mira Journal: Int J Environ Res Public Health Date: 2022-03-04 Impact factor: 3.390