| Literature DB >> 32473695 |
Abstract
Acute right ventricular failure remains the leading cause of mortality associated with acute pulmonary embolism (PE). This article reviews the pathophysiology behind acute right ventricular failure and strategies for managing right ventricular failure in acute PE. Immediate clot reduction via systemic thrombolytics, catheter based procedures, or surgery is always advocated for unstable patients. While waiting to mobilize these resources, it often becomes necessary to support the RV with vasoactive medications. Clinicians should carefully assess volume status and use caution with volume resuscitation. Right ventricular assist devices may have an expanding role in the future.Entities:
Keywords: Cor pulmonale; Extracorporeal membrane oxygenation (ECMO); Massive pulmonary embolism; Pulmonary embolism; Right ventricular failure; Right ventricular support device (RVAD)
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Year: 2020 PMID: 32473695 DOI: 10.1016/j.ccc.2020.02.006
Source DB: PubMed Journal: Crit Care Clin ISSN: 0749-0704 Impact factor: 3.598