Literature DB >> 32472252

Do preoperative glycosylated hemoglobin (HbA1C) and random blood glucose levels predict wound healing complications following exodontia in type 2 diabetes mellitus patients?-a prospective observational study.

B Krishnan1, G Arun Prasad2, R Saravanan2, B Madhan2, T Kadhiravan3.   

Abstract

BACKGROUND: Many dental surgeons consider a type 2 diabetic patient to be at higher risk for wound healing complications following exodontia. Random blood glucose (RBG) and glycosylated hemoglobin (HbA1C) values help the surgeon determine the glycemic control and assess if the patient can undergo the surgical procedure.
OBJECTIVES: The purpose of this study was to analyze if preoperative HbA1C and RBG testing could predict the risk of wound healing and infectious complications in type 2 DM patients undergoing exodontia in an office setting.
METHODS: This prospective observational study included 133 type 2 diabetic patients and age- and gender-matched non-diabetic patients undergoing exodontia. Preoperative HbA1C values and random blood glucose levels were obtained for patients in both groups. Wound healing and infectious complications and additional interventions performed were recorded.
RESULTS: Duration of diabetes ranged from 1 to 25 years. 80.5% of diabetics were treated with oral hypoglycemics. A vast majority of patients in both groups underwent extraction of only a single tooth. There was no significant difference in non-infectious complications between the two groups. The absolute risk of infectious complications in diabetics was 10.5% compared to a 6.8% risk among the control group. Age, RBG values, HbA1C, duration of DM, and number and nature of exodontia performed did not show any statistical significance.
CONCLUSION: This study observed a slight, but not statistically significant increase in the risk of infectious complications in type 2 DM patients undergoing exodontia. Surgical site infections were amenable to surgical drainage with or without oral antibiotics on an outpatient basis with favorable healing outcomes. CLINICAL RELEVANCE: The RBG and HbA1C values were not significantly associated with risk of infectious complications. Resorting to prophylactic antibiotics and warning about possible adverse healing for routine exodontia in type 2 DM patients is unnecessary.

Entities:  

Keywords:  Dentoalveolar; Diabetes; Exodontia; Extraction; Healing; Oral surgery

Year:  2020        PMID: 32472252     DOI: 10.1007/s00784-020-03349-7

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  3 in total

Review 1.  The effectiveness of systemic antibiotic prophylaxis in preventing local complications after tooth extraction. A systematic review.

Authors:  Saverio Marchionni; Paolo Toti; Antonio Barone; Ugo Covani; Marco Esposito
Journal:  Eur J Oral Implantol       Date:  2017       Impact factor: 3.123

2.  Validity of random blood glucose as a predictor of the quality of glycaemic control by glycated haemoglobin in out-patient diabetic patients at Kenyatta National Hospital.

Authors:  F C F Otieno; L Ng'ang'a; M Kariuki
Journal:  East Afr Med J       Date:  2002-09

3.  Epidemiology of type 2 diabetes: Indian scenario.

Authors:  V Mohan; S Sandeep; R Deepa; B Shah; C Varghese
Journal:  Indian J Med Res       Date:  2007-03       Impact factor: 2.375

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.