| Literature DB >> 32472248 |
Gizem Y Yildiz1, Julian S Vilsten1, Amy Siobhan Millard1, Philippe A Chouinard2.
Abstract
We examined whether functional and structural variability in the primary visual area (V1) correlated with autism traits. Twenty-nine participants (16 males; MAge = 26.4 years, SDAge = 4.0 years) completed the autism-spectrum quotient (AQ) questionnaire prior to a magnetic resonance imaging session. The total AQ scores was used to assess the degree of self-reported autism traits. The average functional activation in V1 to visual stimulation and its average grey-matter thickness were calculated. There were no correlations between functional activation in V1 and autism traits. Conversely, grey-matter thickness of the left but not the right V1 correlated with autism traits. We conclude that structural changes in the left V1 could be a marker for the presence of autism traits.Entities:
Keywords: Autism-spectrum quotient (AQ); Grey-matter thickness; Magnetic resonance imaging (MRI); Primary visual area (V1); Retinotopy
Mesh：
Year: 2021 PMID： 32472248 DOI： 10.1007/s10803-020-04553-w
Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257