Literature DB >> 32470402

SnapShot: Ferroptosis.

Kamyar Hadian1, Brent R Stockwell2.   

Abstract

Ferroptosis is a regulated form of cell death that occurs when phospholipids with polyunsaturated fatty acyl tails are oxidized in an iron-dependent manner. Research in recent years has uncovered complex cellular networks that induce and suppress lethal lipid peroxidation. This SnapShot provides an overview of ferroptosis-related pathways, including relevant biomolecules and small-molecule modulators regulating them.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID： 32470402      PMCID： PMC8157339          DOI： 10.1016/j.cell.2020.04.039

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  9 in total

1.  FSP1 is a glutathione-independent ferroptosis suppressor.

Authors:  Sebastian Doll; Florencio Porto Freitas; Ron Shah; Maceler Aldrovandi; Milene Costa da Silva; Irina Ingold; Andrea Goya Grocin; Thamara Nishida Xavier da Silva; Elena Panzilius; Christina H Scheel; André Mourão; Katalin Buday; Mami Sato; Jonas Wanninger; Thibaut Vignane; Vaishnavi Mohana; Markus Rehberg; Andrew Flatley; Aloys Schepers; Andreas Kurz; Daniel White; Markus Sauer; Michael Sattler; Edward William Tate; Werner Schmitz; Almut Schulze; Valerie O'Donnell; Bettina Proneth; Grzegorz M Popowicz; Derek A Pratt; José Pedro Friedmann Angeli; Marcus Conrad
Journal:  Nature       Date:  2019-10-21       Impact factor: 49.962

2.  Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export.

Authors:  Caitlin W Brown; John J Amante; Peter Chhoy; Ameer L Elaimy; Haibo Liu; Lihua Julie Zhu; Christina E Baer; Scott J Dixon; Arthur M Mercurio
Journal:  Dev Cell       Date:  2019-11-14       Impact factor: 12.270

Review 3.  Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Authors:  Brent R Stockwell; José Pedro Friedmann Angeli; Hülya Bayir; Ashley I Bush; Marcus Conrad; Scott J Dixon; Simone Fulda; Sergio Gascón; Stavroula K Hatzios; Valerian E Kagan; Kay Noel; Xuejun Jiang; Andreas Linkermann; Maureen E Murphy; Michael Overholtzer; Atsushi Oyagi; Gabriela C Pagnussat; Jason Park; Qitao Ran; Craig S Rosenfeld; Konstantin Salnikow; Daolin Tang; Frank M Torti; Suzy V Torti; Shinya Toyokuni; K A Woerpel; Donna D Zhang
Journal:  Cell       Date:  2017-10-05       Impact factor: 41.582

4.  Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis.

Authors:  Yilong Zou; Haoxin Li; Emily T Graham; Amy A Deik; John K Eaton; Wenyu Wang; Gerardo Sandoval-Gomez; Clary B Clish; John G Doench; Stuart L Schreiber
Journal:  Nat Chem Biol       Date:  2020-02-17       Impact factor: 15.040

5.  The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression.

Authors:  Guang Lei; Yilei Zhang; Pranavi Koppula; Xiaoguang Liu; Jie Zhang; Steven H Lin; Jaffer A Ajani; Qin Xiao; Zhongxing Liao; Hui Wang; Boyi Gan
Journal:  Cell Res       Date:  2020-01-16       Impact factor: 25.617

6.  The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

Authors:  Kirill Bersuker; Joseph M Hendricks; Zhipeng Li; Leslie Magtanong; Breanna Ford; Peter H Tang; Melissa A Roberts; Bingqi Tong; Thomas J Maimone; Roberto Zoncu; Michael C Bassik; Daniel K Nomura; Scott J Dixon; James A Olzmann
Journal:  Nature       Date:  2019-10-21       Impact factor: 49.962

7.  Energy-stress-mediated AMPK activation inhibits ferroptosis.

Authors:  Hyemin Lee; Fereshteh Zandkarimi; Yilei Zhang; Jitendra Kumar Meena; Jongchan Kim; Li Zhuang; Siddhartha Tyagi; Li Ma; Thomas F Westbrook; Gregory R Steinberg; Daisuke Nakada; Brent R Stockwell; Boyi Gan
Journal:  Nat Cell Biol       Date:  2020-02-06       Impact factor: 28.824

8.  GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling.

Authors:  Vanessa A N Kraft; Carla T Bezjian; Susanne Pfeiffer; Larissa Ringelstetter; Constanze Müller; Fereshteh Zandkarimi; Juliane Merl-Pham; Xuanwen Bao; Natasa Anastasov; Johanna Kössl; Stefanie Brandner; Jacob D Daniels; Philippe Schmitt-Kopplin; Stefanie M Hauck; Brent R Stockwell; Kamyar Hadian; Joel A Schick
Journal:  ACS Cent Sci       Date:  2019-12-27       Impact factor: 14.553

9.  Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers.

Authors:  Ling F Ye; Kunal R Chaudhary; Fereshteh Zandkarimi; Andrew D Harken; Connor J Kinslow; Pavan S Upadhyayula; Athanassios Dovas; Dominique M Higgins; Hui Tan; Yan Zhang; Manuela Buonanno; Tony J C Wang; Tom K Hei; Jeffrey N Bruce; Peter D Canoll; Simon K Cheng; Brent R Stockwell
Journal:  ACS Chem Biol       Date:  2020-01-14       Impact factor: 4.634
  9 in total
  44 in total

1.  Cancer cells stock up in lymph vessels to survive.

Authors:  Barbara M Grüner; Sarah-Maria Fendt
Journal:  Nature       Date:  2020-09       Impact factor: 49.962

2.  Inhibition of ALG3 stimulates cancer cell immunogenic ferroptosis to potentiate immunotherapy.

Authors:  Pei Liu; Cha Lin; Zheyu Liu; Chenchen Zhu; Zhongda Lin; Dan Xu; Jian Chen; Qian Huang; Chuan-Yuan Li; Linlin Hou; Ji-An Pan; Xinjian Liu
Journal:  Cell Mol Life Sci       Date:  2022-06-08       Impact factor: 9.261

3.  Hemorrhage-Induced Sphingosine Kinase 1 Contributes to Ferroptosis-Mediated Secondary Brain Injury in Intracerebral Hemorrhage.

Authors:  Xiaojun Diao; Qi Cui; Ning Tian; Zixian Zhou; Wenjing Xiang; Yanlin Jiang; Jungang Deng; Hongzhan Liao; Xiaohui Lin; Qinghua Li; Rujia Liao
Journal:  Mol Neurobiol       Date:  2022-01-07       Impact factor: 5.590

4.  Synthesis and Optimization of Nitroxide-Based Inhibitors of Ferroptotic Cell Death in Cancer Cells and Macrophages.

Authors:  Manwika Charaschanya; Taber S Maskrey; Matthew G LaPorte; Jelena M Janjic; Peter Wipf
Journal:  ACS Med Chem Lett       Date:  2022-02-04       Impact factor: 4.345

Review 5.  Iron homeostasis and organismal aging.

Authors:  Rola S Zeidan; Sung Min Han; Christiaan Leeuwenburgh; Rui Xiao
Journal:  Ageing Res Rev       Date:  2021-11-09       Impact factor: 10.895

6.  A roadmap to creating ferroptosis-based medicines.

Authors:  Kamyar Hadian; Brent R Stockwell
Journal:  Nat Chem Biol       Date:  2021-11       Impact factor: 15.040

7.  CPLX2 Regulates Ferroptosis and Apoptosis Through NRF2 Pathway in Human Hepatocellular Carcinoma Cells.

Authors:  Juan Zhao; Hui Li; Xiao-Lan Zhong; Pei-Yan Xu; Li-Jun Du; Ping Fang; Li-Juan Tan; Mei-Juan Li; Cheng-Fang Zhang; Tian-Sheng Cao
Journal:  Appl Biochem Biotechnol       Date:  2022-09-15       Impact factor: 3.094

8.  UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.

Authors:  Jingyi Li; Xiangting Tang; Xueer Tu; Zhe Jin; Hao Dong; Qi Yang; Ting Yao; Zezheng Pan
Journal:  Cell Stress Chaperones       Date:  2022-06-21       Impact factor: 3.827

9.  MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma.

Authors:  Yuxiong Lu; Qing Yang; Yubin Su; Yin Ji; Guobang Li; Xianzhi Yang; Liyan Xu; Zhaoliang Lu; Jiajun Dong; Yi Wu; Jin-Xin Bei; Chaoyun Pan; Xiaoqiong Gu; Bo Li
Journal:  Cell Death Dis       Date:  2021-05-19       Impact factor: 8.469

Review 10.  Emerging mechanisms and targeted therapy of ferroptosis in cancer.

Authors:  Haiyan Wang; Yan Cheng; Chao Mao; Shuang Liu; Desheng Xiao; Jun Huang; Yongguang Tao
Journal:  Mol Ther       Date:  2021-03-29       Impact factor: 12.910
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