Literature DB >> 32468891

Use of Steroid-Eluting Stents after Endoscopic Repair of Choanal Atresia: A Case Series with Review.

Lyndy J Wilcox1,2, Matthew M Smith1,3, Alessandro de Alarcon1,3, Madison Epperson4, Hayley Born3, Catherine K Hart1,3.   

Abstract

OBJECTIVE(S): To describe a single institution's experience with the use of steroid-eluting stents after endoscopic transnasal repair of choanal atresia.
METHODS: A case series with review of children who underwent choanal atresia repair at a tertiary children's hospital from June 2017 to January 2018 was performed. Those who had a mometasone drug-eluting stent (Propel® Mini, Intersect ENT Inc., Palo Alto, CA) placed after primary or secondary choanal atresia repair at our institution were included. The primary outcome measure was need for revision surgery due to stenosis. Postoperative regimens, duration of stenting, and need for return to the operating room (OR) were also assessed.
RESULTS: Five patients with a median age of 22 months at the time of repair met inclusion criteria. Two (40%) had bilateral atresia and 3 (60%) had confirmed CHARGE syndrome. A total of 6 mometasone drug-eluting stents were used in the 5 cases. Three patients were reassessed at least once in the OR; however, the majority (57.1%) of postoperative evaluations were able to be performed in the office or bedside setting. The first and last evaluations occurred a mean of 14 and 124 days after surgery, respectively. There were no instances of restenosis, repeat surgical interventions, or stent-related complications noted.
CONCLUSION: Placement of a mometasone drug-eluting stent is a promising method to improve postoperative results and management of choanal atresia repair by limiting the need for repeat anesthetics and OR procedures, as well as the complications of traditional stents.

Entities:  

Keywords:  choanal atresia; congenital anomalies; endoscopic repair; mometasone fumate; nasal obstruction; steroid-eluting stents

Mesh:

Substances:

Year:  2020        PMID: 32468891     DOI: 10.1177/0003489420928374

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  2 in total

1.  Surgical Management of Choanal Atresia: Two Classic Cases and Review of the Literature.

Authors:  Nicholas A Rossi; Mia Benavidez; Harold S Pine; Shiva Daram; Wasyl Szeremeta
Journal:  Cureus       Date:  2022-04-18

Review 2.  Choanal Atresia Repair With Stents and Flaps: A Systematic Review Article.

Authors:  Hemail M Alsubaie; Wedyan H Almosa; Ali S Al-Qahtani; Osama Margalani
Journal:  Allergy Rhinol (Providence)       Date:  2021-12-17
  2 in total

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