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Literature DB >> 32468670

Control the platelets, control the disease: A novel cystic fibrosis hypothesis.

Siobhan Branfield¹, A Valance Washington¹.

Abstract

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：
Cyclic AMP

Year: 2020 PMID： 32468670 PMCID： PMC7872297 DOI： 10.1111/jth.14868

Source DB: PubMed Journal: J Thromb Haemost ISSN： 1538-7836 Impact factor: 5.824

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31 in total

1. Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.

Authors: Peter G Middleton; Marcus A Mall; Pavel Dřevínek; Larry C Lands; Edward F McKone; Deepika Polineni; Bonnie W Ramsey; Jennifer L Taylor-Cousar; Elizabeth Tullis; François Vermeulen; Gautham Marigowda; Charlotte M McKee; Samuel M Moskowitz; Nitin Nair; Jessica Savage; Christopher Simard; Simon Tian; David Waltz; Fengjuan Xuan; Steven M Rowe; Raksha Jain
Journal: N Engl J Med Date: 2019-10-31 Impact factor: 91.245

2. Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics.

Authors: M J Stutts; B C Rossier; R C Boucher
Journal: J Biol Chem Date: 1997-05-30 Impact factor: 5.157

3. CFTR inhibition mimics the cystic fibrosis inflammatory profile.

Authors: Aura Perez; Amanda C Issler; Calvin U Cotton; Thomas J Kelley; Alan S Verkman; Pamela B Davis
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2006-08-18 Impact factor: 5.464

Review 4. PPARγ as a therapeutic target in cystic fibrosis.

Authors: Johanna F Dekkers; Cornelis K van der Ent; Eric Kalkhoven; Jeffrey M Beekman
Journal: Trends Mol Med Date: 2012-04-09 Impact factor: 11.951

5. Risk factors for bronchiectasis in children with cystic fibrosis.

Authors: Peter D Sly; Catherine L Gangell; Linping Chen; Robert S Ware; Sarath Ranganathan; Lauren S Mott; Conor P Murray; Stephen M Stick
Journal: N Engl J Med Date: 2013-05-23 Impact factor: 91.245

6. Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways.

Authors: Shahryar Saba; Grace Soong; Steven Greenberg; Alice Prince
Journal: Am J Respir Cell Mol Biol Date: 2002-11 Impact factor: 6.914

7. Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.

Authors: Harry G M Heijerman; Edward F McKone; Damian G Downey; Eva Van Braeckel; Steven M Rowe; Elizabeth Tullis; Marcus A Mall; John J Welter; Bonnie W Ramsey; Charlotte M McKee; Gautham Marigowda; Samuel M Moskowitz; David Waltz; Patrick R Sosnay; Christopher Simard; Neil Ahluwalia; Fengjuan Xuan; Yaohua Zhang; Jennifer L Taylor-Cousar; Karen S McCoy
Journal: Lancet Date: 2019-10-31 Impact factor: 79.321

Control the platelets, control the disease: A novel cystic fibrosis hypothesis.

1. Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.

2. Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics.

3. CFTR inhibition mimics the cystic fibrosis inflammatory profile.

Review 4. PPARγ as a therapeutic target in cystic fibrosis.

5. Risk factors for bronchiectasis in children with cystic fibrosis.

6. Bacterial stimulation of epithelial G-CSF and GM-CSF expression promotes PMN survival in CF airways.

7. Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.

8. A critical role for the transient receptor potential channel type 6 in human platelet activation.

9. CFTR is a negative regulator of NFkappaB mediated innate immune response.

10. Important role of platelets in modulating endotoxin-induced lung inflammation in CFTR-deficient mice.

Review 1. The enigmatic nature of the triggering receptor expressed in myeloid cells -1 (TLT- 1).