Literature DB >> 32467637

Outcome of a low-cost glaucoma drainage device with posterior chamber/pars plana insertion of the tube.

Muralidhar Rajamani1, Chitra Ramamurthy2, Shreyas Ramamurthy2, Craig Chaya3, George Puthuran4, Shreesh Kumar2, Ashraya Nayaka2.   

Abstract

INTRODUCTION: The Aurolab aqueous drainage implant (AADI) is a low-cost glaucoma drainage device that is modelled on the Baerveldt glaucoma implant. Studies on AADI have reported absolute success rates of 41.8-93.1% at 1 year. Most studies report on tube placement in the anterior chamber. We report on results of tube insertion in the sulcus/pars plana.
MATERIAL AND METHODS: A retrospective chart review of all patients who had undergone AADI implantation (with insertion of tube in the sulcus/posterior segment) between June 2015 and November 2018 was done. Patients were asked to stop anti-glaucoma medications on the 40th post-operative day.
RESULTS: The mean age was 57.4 ± 13.8 years (n = 30). The mean IOP prior to surgery was 34.4 ± 6.1 mmHg which reduced to 15.4 ± 8.6 mmHg on the 45th post-operative day (p < 0.001). The absolute success at last review was 10% and the qualified success was 80%. The complication rate was 26.7%. Three patients had hypotony related complications noted at/after the 45th day review (none before 40th day). The incidence of ocular motility disturbances was 26.7% though none of the patients reported diplopia. One patient had sideways rotation of the scleral patch graft resulting in tube exposure. This complication was not seen after we shifted to using 9-0 nylon sutures to anchor the graft. Six patients had loss of best corrected visual acuity and one patient developed endophthalmitis. The endophthalmitis was preceded by conjunctival retraction and sloughing off of the scleral patch graft. DISCUSSION: AADI implantation results in a substantial drop in IOP. However, many patients continue to require anti-glaucoma medications. Allowing overlap of scleral/corneal patch graft onto the scleral flap may be effective in preventing peritubular leak. It may be advisable to use 9-0 nylon sutures to secure the scleral patch graft anti-glaucoma medications can be temporarily suspended after the 40th post-operative day to minimize hypotony related complications. Melting of the scleral patch graft may be an early sign of endophthalmitis. It would be prudent to specifically look for ocular motility problems in patients undergoing AADI implantation.

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Year:  2020        PMID: 32467637      PMCID: PMC8026980          DOI: 10.1038/s41433-020-0994-x

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  3 in total

1.  Intermediate-Term Outcomes of an Affordable Aqueous Drainage Implant in Adults with Refractory Glaucoma.

Authors:  George V Puthuran; Paul Palmberg; Hiruni Kaushalya Wijesinghe; Subbaiah R Krishnadas; Alan Robin
Journal:  Ophthalmol Glaucoma       Date:  2019-04-04

2.  Comparison of the changes in corneal endothelial cells after pars plana and anterior chamber ahmed valve implant.

Authors:  Ji Won Seo; Jong Yeon Lee; Dong Heun Nam; Dae Yeong Lee
Journal:  J Ophthalmol       Date:  2015-01-28       Impact factor: 1.909

3.  Prospective cohort study of corneal endothelial cell loss after Baerveldt glaucoma implantation.

Authors:  Kentaro Iwasaki; Shogo Arimura; Yuji Takihara; Yoshihiro Takamura; Masaru Inatani
Journal:  PLoS One       Date:  2018-07-26       Impact factor: 3.240

  3 in total
  2 in total

1.  Surgical outcomes of the Aurolab aqueous drainage implant (AADI) versus the Ahmed glaucoma valve for refractory paediatric glaucoma in Middle Eastern children.

Authors:  Abdullah M Khan; Khabir Ahmad; Motazz Alarfaj; Humoud Alotaibi; Ahmad AlJaloud; Rizwan Malik
Journal:  BMJ Open Ophthalmol       Date:  2021-11-10

2.  Pars plana Aurolab aqueous drainage implantation for refractory glaucoma: Outcome of a new modified technique.

Authors:  Mohideen A Kader; Shylesh B Dabke; Aakriti G Shukla; Venugopal Reddy; Syed M Abdul Khadar; Devendra Maheshwari; Rengappa Ramakrishnan
Journal:  Indian J Ophthalmol       Date:  2022-03       Impact factor: 2.969

  2 in total

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