Literature DB >> 32467548

Silent microaspirations: The forerunner to the diagnosis of bulbar onset myasthenia gravis in a young woman.

T L Tan1, H J Tan2, C F Cheah3, R Kumaresh4, N A Azzahra5.   

Abstract

Recurrent pneumonia warrants a diligent work-up to identify the underlying cause that perpetuates the disease process. Insidious bulbar dysfunction is arguably the most devastating as it would be diagnosed late after significant pulmonary complications due to chronic micro-aspiration. Bulbar disorder should be considered as the potential aetiology of recurrent pulmonary infections in the young population after excluding immunodeficiency disorder and respiratory anatomical anomaly. This report illustrates a rare case of bulbar onset myasthenia gravis which manifested as focal bronchiolectasis due to recurrent undiagnosed aspiration pneumonia three years earlier. Absence of hallmark features of Myasthenia Gravis (MG) such as ptosis, opthalmoplegia and proximal muscle weakness contributed to the diagnostic delay and challenges in this case. The diagnosis was established with the collaboration of multidisciplinary teams. Subsequent correct therapeutic interventions resulted in remarkable recovery in functional status and prevented her from further aspiration in the long run.

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Year:  2020        PMID: 32467548

Source DB:  PubMed          Journal:  Med J Malaysia        ISSN: 0300-5283


  1 in total

1.  The Eldest Female Case of Myasthenia Gravis with an Unusual Presentation: Aspiration Pneumonia as the Initial Manifestation.

Authors:  Yuya Masuda; Teru Kumagi; Noriyuki Miyaue; Yuko Hosokawa; Hayato Yabe
Journal:  Cureus       Date:  2021-11-05
  1 in total

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