Literature DB >> 32467114

Advanced myeloma masquerading as chronic shoulder pain in a 48-year-old man: a diagnostic dilemma.

Rajarshi Bhadra1, Teodora Nikova2, Meyappan Somasundaram3, Keyvan Ravakhah3.   

Abstract

Although solitary plasmacytomas may occasionally present as collar bone swellings or fractures, multiple myeloma involving clavicle is extremely rare. Ten to forty per cent of multiple myeloma cases are asymptomatic and are incidental diagnoses. Our case report describes an entirely benign presentation like chronic shoulder pain masquerading advanced myeloma, thereby posing a significant diagnostic dilemma. We present a 48-year-old man who presented with chronic bilateral shoulder pain with no history of trauma and was eventually diagnosed with advanced multiple myeloma and pathologic fracture of the right clavicle. It is, therefore, evident that a low threshold for suspicion can lead to early diagnosis and initiation of treatment and better survival. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  cancer - see oncology; malignant disease and immunosuppression; monoclonal gammopathy of undetermined significance associated neuropathy; renal system

Mesh:

Substances:

Year:  2020        PMID: 32467114      PMCID: PMC7259869          DOI: 10.1136/bcr-2019-231219

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  16 in total

1.  Collar bone swellings--a varied presentation of multiple myeloma.

Authors:  S V Justin Arockiaraj; G Gopisankar Balaji; Bandikala Vidyasagar
Journal:  Jpn J Clin Oncol       Date:  2014-01       Impact factor: 3.019

Review 2.  Multiple myeloma.

Authors:  Antonio Palumbo; Kenneth Anderson
Journal:  N Engl J Med       Date:  2011-03-17       Impact factor: 91.245

3.  Autologous transplantation and maintenance therapy in multiple myeloma.

Authors:  Antonio Palumbo; Federica Cavallo; Francesca Gay; Francesco Di Raimondo; Dina Ben Yehuda; Maria Teresa Petrucci; Sara Pezzatti; Tommaso Caravita; Chiara Cerrato; Elena Ribakovsky; Mariella Genuardi; Anna Cafro; Magda Marcatti; Lucio Catalano; Massimo Offidani; Angelo Michele Carella; Elena Zamagni; Francesca Patriarca; Pellegrino Musto; Andrea Evangelista; Giovannino Ciccone; Paola Omedé; Claudia Crippa; Paolo Corradini; Arnon Nagler; Mario Boccadoro; Michele Cavo
Journal:  N Engl J Med       Date:  2014-09-04       Impact factor: 91.245

4.  Pathologic fractures correlate with reduced survival in patients with malignant bone disease.

Authors:  Fred Saad; Allan Lipton; Richard Cook; Yin-Miao Chen; Matthew Smith; Robert Coleman
Journal:  Cancer       Date:  2007-10-15       Impact factor: 6.860

5.  Presenting signs and symptoms in multiple myeloma: high percentages of stage III among patients without apparent myeloma-associated symptoms.

Authors:  F Ong; J Hermans; E M Noordijk; P W Wijermans; J C Kluin-Nelemans
Journal:  Ann Hematol       Date:  1995-03       Impact factor: 3.673

6.  Multiple myeloma: a clinicopathologic study of 62 consecutively autopsied cases.

Authors:  S B Kapadia
Journal:  Medicine (Baltimore)       Date:  1980-09       Impact factor: 1.889

Review 7.  Multiple myeloma: diagnosis and treatment.

Authors:  Konrad C Nau; William D Lewis
Journal:  Am Fam Physician       Date:  2008-10-01       Impact factor: 3.292

Review 8.  Multiple myeloma: clinical review and diagnostic imaging.

Authors:  Edgardo J C Angtuaco; Athanasios B T Fassas; Ronald Walker; Rajesh Sethi; Bart Barlogie
Journal:  Radiology       Date:  2004-02-27       Impact factor: 11.105

9.  Case report 621. Multiple myeloma (IgD) in a 28-year-old woman.

Authors:  G Hermann; I F Abdelwahab; B D Berson; M L Greenberg; C J Palestro
Journal:  Skeletal Radiol       Date:  1990       Impact factor: 2.199

Review 10.  Myeloma bone disease: Pathophysiology and management.

Authors:  Rebecca Silbermann; G David Roodman
Journal:  J Bone Oncol       Date:  2013-04-18       Impact factor: 4.072

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