| Literature DB >> 32464192 |
Santoshi Naik1, Abhijeet Pandey1, Shaila A Lewis1, Bola Sadashiva Satish Rao2, Srinivas Mutalik3.
Abstract
In most retinal diseases, neuronal loss is the main cause of vision loss. Neuroprotection is the alteration of neurons and/or their environment to encourage the survival and function of the neurons, especially in environments that are deleterious to the neuronal health. The area of neuroprotection progresses with a therapeutically-based hope of improving vision and clinical outcomes for patients through the developments in neurotrophic therapy, antioxidative therapy, anti-excitotoxic, anti-ischemic, anti-inflammatory, and anti-apoptotic care. In this review, we summarize the various neuroprotection strategies for the treatment of glaucoma, genetics of glaucoma and the role of various nanoplatforms in the treatment of glaucoma.Entities:
Keywords: Genetics; Glaucoma; Nanoplatforms; Neuroprotection
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Year: 2020 PMID: 32464192 DOI: 10.1016/j.ejphar.2020.173208
Source DB: PubMed Journal: Eur J Pharmacol ISSN: 0014-2999 Impact factor: 4.432