Literature DB >> 32463070

Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting.

M N Sabbagh1, M Boada, S Borson, P M Doraiswamy, B Dubois, J Ingram, A Iwata, A P Porsteinsson, K L Possin, G D Rabinovici, B Vellas, S Chao, A Vergallo, H Hampel.   

Abstract

Emerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers. A wide variety of apps, wearables, and new digital technologies are either available or in development for the detection of mild cognitive impairment (MCI), a risk factor for dementia. Two categories of novel methodologies may be considered: passive technologies (which monitor a user's behavior without active user input) and interactive assessments (which require active user input). Such examinations can be self-administered, supervised by a caregiver, or conducted by an informant at home or outside of a clinical setting. These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. Although direct-to-consumer cognitive assessment is associated with its own barriers, including test validation, user experience, and technological concerns, it is conceivable that these issues can be addressed so that a large-scale, self-assessed cognitive evaluation that would represent an initial cognitive screen may be feasible in the future.

Entities:  

Keywords:  Alzheimer’s disease; cognitive screening; digital consumer; mild cognitive impairment

Mesh:

Year:  2020        PMID: 32463070     DOI: 10.14283/jpad.2020.22

Source DB:  PubMed          Journal:  J Prev Alzheimers Dis        ISSN: 2274-5807


  6 in total

Review 1.  Toward noninvasive brain stimulation 2.0 in Alzheimer's disease.

Authors:  Arianna Menardi; Simone Rossi; Giacomo Koch; Harald Hampel; Andrea Vergallo; Michael A Nitsche; Yaakov Stern; Barbara Borroni; Stefano F Cappa; Maria Cotelli; Giulio Ruffini; Georges El-Fakhri; Paolo M Rossini; Brad Dickerson; Andrea Antal; Claudio Babiloni; Jean-Pascal Lefaucheur; Bruno Dubois; Gustavo Deco; Ulf Ziemann; Alvaro Pascual-Leone; Emiliano Santarnecchi
Journal:  Ageing Res Rev       Date:  2021-12-30       Impact factor: 11.788

2.  Diagnostic accuracy of the Cogstate Brief Battery for prevalent MCI and prodromal AD (MCI A+ T+ ) in a population-based sample.

Authors:  Eva C Alden; Shehroo B Pudumjee; Emily S Lundt; Sabrina M Albertson; Mary M Machulda; Walter K Kremers; Clifford R Jack; David S Knopman; Ronald C Petersen; Michelle M Mielke; Nikki H Stricker
Journal:  Alzheimers Dement       Date:  2021-03-01       Impact factor: 16.655

3.  A novel computer adaptive word list memory test optimized for remote assessment: Psychometric properties and associations with neurodegenerative biomarkers in older women without dementia.

Authors:  Nikki H Stricker; John L Stricker; Aimee J Karstens; Jennifer R Geske; Julie A Fields; Jason Hassenstab; Christopher G Schwarz; Nirubol Tosakulwong; Heather J Wiste; Clifford R Jack; Kejal Kantarci; Michelle M Mielke
Journal:  Alzheimers Dement (Amst)       Date:  2022-03-09

4.  A Comparison of Cross-Sectional and Longitudinal Methods of Defining Objective Subtle Cognitive Decline in Preclinical Alzheimer's Disease Based on Cogstate One Card Learning Accuracy Performance.

Authors:  Shehroo B Pudumjee; Emily S Lundt; Sabrina M Albertson; Mary M Machulda; Walter K Kremers; Clifford R Jack; David S Knopman; Ronald C Petersen; Michelle M Mielke; Nikki H Stricker
Journal:  J Alzheimers Dis       Date:  2021       Impact factor: 4.472

5.  The Sars-Cov-2 Pandemic and the Brave New Digital World of Environmental Enrichment to Prevent Brain Aging and Cognitive Decline.

Authors:  H Hampel; A Vergallo
Journal:  J Prev Alzheimers Dis       Date:  2020

6.  Environmental Distractions during Unsupervised Remote Digital Cognitive Assessment.

Authors:  E N Madero; J Anderson; N T Bott; A Hall; D Newton; N Fuseya; J E Harrison; J R Myers; J M Glenn
Journal:  J Prev Alzheimers Dis       Date:  2021
  6 in total

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