Literature DB >> 32462465

Testicular tumours in children: an approach to diagnosis and management with pathologic correlation.

Cinta Sangüesa1, Diana Veiga2, Margarita Llavador3, Agustín Serrano4.   

Abstract

Testicular tumours are rare in children. Painless scrotal mass is the most frequent clinical presentation. Tumoural markers (alpha-fetoprotein, beta-human gonadotropin chorionic) and hormone levels (testosterone) contribute to the diagnosis and management of a testicular mass in boys. Ultrasonography is the best imaging modality to study testicular tumours. A benign tumour is suggested when ultrasonography shows a mainly cystic component, well-defined borders, echogenic rim or normal to increased echogenicity lesion when compared to the healthy testicular parenchyma. Malignant tumour is suspected when ultrasonography shows inhomogeneous, hypoechoic, not well-circumscribed or diffuse infiltration lesion. However, these ultrasonographic findings may overlap. Colour Doppler, power Doppler, elastography and contrast-enhanced ultrasonography are useful complementary methods to characterise the focal testicular lesions. Chest computerised tomography and abdominopelvic magnetic resonance are necessary to establish the extension in case of malignant proved tumours.Benign tumours are more frequent in prepuberal boys and malignant tumours in pubertal boys. Mature teratoma prepubertal-type is the most common histologic type. Testicular sparing surgery is the choice in benign tumours. Radical inguinal orchiectomy is indicated in malignant tumours. Prognostic is excellent.The purpose of our study is to show an approach to the diagnosis and management of the most frequent testicular tumours in children according to clinical manifestations, imaging findings and tumour markers levels based on histologically confirmed tumours in our hospital.

Entities:  

Keywords:  Alpha-fetoprotein; Child; Testicular neoplasm; Ultrasonography, Doppler

Year:  2020        PMID: 32462465     DOI: 10.1186/s13244-020-00867-6

Source DB:  PubMed          Journal:  Insights Imaging        ISSN: 1869-4101


  6 in total

Review 1.  Ovarian and non-ovarian teratomas: a wide spectrum of features.

Authors:  Tsukasa Saida; Kensaku Mori; Tomohiko Masumoto; Sodai Hoshiai; Toshitaka Ishiguro; Masafumi Sakai; Tadashi Hara; Hiroyuki Ochi; Toyomi Satoh; Manabu Minami
Journal:  Jpn J Radiol       Date:  2020-09-01       Impact factor: 2.374

Review 2.  Normal and Premature Adrenarche.

Authors:  Robert L Rosenfield
Journal:  Endocr Rev       Date:  2021-11-16       Impact factor: 19.871

3.  Leydig Cell Tumor-Induced Gonadotropin-Independent Precocious Puberty Progressing to Gonadotropin-Dependent Precocious Puberty Post Orchiectomy: Out of the Frying Pan Into the Fire.

Authors:  Pankaj Singhania; Rana Bhattacharjee; Partha Pratim Chakraborty; Subhankar Chowdhury
Journal:  Cureus       Date:  2022-01-12

4.  Malignant testicular tumors in children: A single institution's 12-year experience.

Authors:  Chia-Chi Chiu; Tang-Her Jaing; Jin-Yao Lai; Shih-Hsiang Chen; Tsung-Yen Chang; Chuen Hsueh; Yu-Chuan Wen; Pei-Kwei Tsay
Journal:  Medicine (Baltimore)       Date:  2022-07-22       Impact factor: 1.817

Review 5.  [Inguinal and Scrotal Diseases in Children and Adolescents].

Authors:  Jaeyoung Lee; Youngtong Kim; Sungshick Jou; Chanho Park
Journal:  J Korean Soc Radiol       Date:  2022-07-25

Review 6.  The role of scrotal ultrasonography from infancy to puberty.

Authors:  Matteo Spaziani; Claudio Lecis; Chiara Tarantino; Emilia Sbardella; Carlotta Pozza; Daniele Gianfrilli
Journal:  Andrology       Date:  2021-06-11       Impact factor: 3.842

  6 in total

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