| Literature DB >> 32462116 |
Philipp Sprengholz1, Cornelia Betsch1.
Abstract
BACKGROUND: Low vaccine uptake results in regular outbreaks of severe diseases, such as measles. Selective mandates, e.g. making measles vaccination mandatory (as currently implemented in Germany), could offer a viable solution to the problem. However, prior research has shown that making only some vaccinations mandatory, while leaving the rest to voluntary decisions, can result in psychological reactance (anger) and decreased uptake of voluntary vaccines. Since communicating the concept of herd immunity has been shown to increase willingness to vaccinate, this study assessed whether it can buffer such reactance effects.Entities:
Keywords: Reactance; Selective mandates; Vaccination
Year: 2020 PMID: 32462116 PMCID: PMC7240331 DOI: 10.1016/j.eclinm.2020.100352
Source DB: PubMed Journal: EClinicalMedicine ISSN: 2589-5370
Fig. 1CONSORT flow diagram. Note: Non-applicable elements of the CONSORT template were removed. There was no time interval between intervention allocation and follow-up.
Fictitious diseases presented in the first and second scenarios.
| Cornosis | Holtosis |
|---|---|
| Cornosis spreads through the air from one person to another. When infected, people like you normally suffer from fever and rash. Restlessness and dizziness are also common. For most adults and children being 3 years or older, symptoms disappear within two weeks. | Holtosis spreads through the air from one person to another. When infected, people like you normally suffer from seizures and stomach ache. Qualm and lack of concentration are also common. For most adults and children being 3 years or older, symptoms disappear within two weeks. |
| But for children below 3 years, symptoms are much worse. They often face severe vomiting and diarrhea with extreme dehydration, potentially leading to kidney failure. | But for children below 3 years, symptoms are much worse. They often face severe tinnitus and ague, potentially leading to palsy of separate parts of the body. |
| There is a vaccination against Cornosis. This vaccination effectively protects against infection but is not available for those at high risk – children below 3 years cannot get vaccinated. | There is a vaccination against Holtosis. This vaccination effectively protects against infection but is not available for those at high risk – children below 3 years cannot get vaccinated. |
| For those who can get vaccinated, adverse events such as fever, rash, restlessness, dizziness, vomiting and dehydration have been reported. | For those who can get vaccinated, adverse events such as seizures, stomach ache, qualm, lack of concentration, tinnitus and ague have been reported. |
Note: For each participant, the choice of disease for the first scenario was made at random, the disease not drawn becoming the one used in the second scenario. Vaccination was mandatory or voluntary in the first scenario, depending on policy condition, and always voluntary in the second scenario. Full materials are available at https://osf.io/pnjs9/.
Moderated mediation regression analysis.
| Constant | 0.155 | 2.133 | 2.740 | |
| Policy (a1) | 0.226 | 0.667 | 1.552 | |
| Communication condition (a2) | 0.213 | 0.294 | ||
| Policy × Communication condition (a3) | 0.306 | |||
| Constant | 0.412 | 16.820 | 18.436 | |
| Policy (c) | 0.454 | 0.443 | 1.323 | |
| Anger (b) | 0.118 | |||
| Herd immunity communication ((a1 + a3) * b) | 0.212 | 0.076 | ||
| No herd immunity communication (a1 * b) | 0.262 | |||
Note: Policy condition: 0 = voluntary vaccination, 1 = selective mandate. Communication condition: 0 = no herd immunity communication, 1 = herd immunity communication. Both mediator and dependent variable models are based on OLS regressions. Letters in parentheses refer to the coefficients displayed in Fig. 3. Bold values are statistically significant with p < .05. CI lower and CI upper are the lower and upper endpoints of the 95% confidence interval.
Fig. 2Effects of policy and communication on anger. Note: Selective vaccination mandates caused higher ratings of anger than voluntary vaccinations did. When information about herd immunity was given, this effect did not appear. Anger was assessed as a mean of angriness, annoyance, and irritation after the first vaccination. Error bars indicate 95% confidence intervals. Further analysis revealed that higher levels of anger had a significant negative effect on the intention to receive a voluntary vaccination (middle panel of Table 1).
Fig. 3Moderated mediation model. Note: This model explores whether anger elicited by the selective mandate (vs. voluntary vaccination) policy mediates the relation between policy and the intention to get the second voluntary vaccine—and whether this is only the case when herd immunity has been communicated. The indices in the conceptual diagram (left) and statistical model (right) refer to the effects indicated in Table 2. The results show a significant conditional indirect effect (policy on intention via anger, but only when herd immunity was not communicated).