Literature DB >> 32458469

The Efficacy and Safety of CO2 Laser Treatment for Sexual Function and Vaginal Laxity Improvement in Pre-Menopausal Women.

Roy Lauterbach1, Hanin Dabaja1, Emad Matanes1, Ilan Gruenwald2, Lior Lowenstein1.   

Abstract

BACKGROUND AND OBJECTIVES: Vaginal laxity lacks standardized diagnosis and severity criteria. It is considered as a subjective complaint that reflects decreased sexual satisfaction due to vaginal loosening. Treatment modalities have included physiotherapy and plastic surgery. Recently, laser treatments have also gained popularity as a means of relieving gynecological complaints such as pelvic organ prolapse, stress urinary incontinence, and genitourinary syndrome of menopause. The aim of the current study was to evaluate the efficacy of CO2 laser treatment in women for whom a decrease in sexual sensation during intercourse and vaginal loosening were their primary complaints. STUDY DESIGN/
MATERIALS AND METHODS: For this prospective study, women with reported vaginal laxity and decreased sensation during intercourse were recruited from the Sexual Dysfunction Clinic in our health care campus. Each participant received three outpatient treatments with laser therapy, according to the same protocol. Treatment efficacy was assessed by changes in the Vaginal Health Index (VHI) and Female Sexual Function Index (FSFI).
RESULTS: Overall, 84 pre-menopause women, with a mean age of 47.7 years, were included in the study. Mean VHI and FSFI were increased significantly at 3 months post-treatment and decreased again at 6 months post-treatment: 11.8 ± 1.6, 13.5 ± 1.1, and 11.8 ± 1.2, respectively, P = 0.013; and 21.3 ± 1.7, 29.9 ± 1.6, and 22.5 ± 1.8, respectively, P = 0.022. The rate of sexual intercourse doubled during the period of maximal treatment effect (P < 0.0001).
CONCLUSIONS: CO2 laser treatment has both a statistically and clinically significant effect on participants' complaints and sex-life, which wanes by 6 months post-treatment. Laser therapy seems to be safe in the short term, with no serious adverse events reported in the current study. Further studies are warranted to determine the long-term safety and the efficacy of maintenance laser treatments. Lasers Surg. Med.
© 2020 Wiley Periodicals LLC. © 2020 Wiley Periodicals LLC.

Entities:  

Keywords:  CO2 laser; efficacy; safety; sensation; vaginal laxity

Year:  2020        PMID: 32458469     DOI: 10.1002/lsm.23263

Source DB:  PubMed          Journal:  Lasers Surg Med        ISSN: 0196-8092            Impact factor:   4.025


  3 in total

1.  The efficacy and safety of a single maintenance laser treatment for stress urinary incontinence: a double-blinded randomized controlled trial.

Authors:  Roy Lauterbach; Saar Aharoni; Naphtali Justman; Naama Farago; Ilan Gruenwald; Lior Lowenstein
Journal:  Int Urogynecol J       Date:  2022-02-23       Impact factor: 2.894

2.  The Fractional CO2 Laser for the Treatment of Genitourinary Syndrome of Menopause: A Prospective Multicenter Cohort Study.

Authors:  Jingran Li; Huan Li; Yanfei Zhou; Meiqing Xie; Yali Miao; Luwen Wang; Yan Zhao; Ting Ying; Yan Hu; Yu Chen; Yaxiao Chen; Xiuli Sun; Jianliu Wang
Journal:  Lasers Surg Med       Date:  2020-11-19       Impact factor: 4.025

3.  Nonablative, Noncoagulative Multipolar Radiofrequency and Pulsed Electromagnetic Field Treatment Improves Vaginal Laxity and Sexual Function.

Authors:  Yegor Kolodchenko
Journal:  Womens Health Rep (New Rochelle)       Date:  2021-07-27
  3 in total

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