Literature DB >> 324577

Randomised controlled trial of treatment for mild hypertension: design and pilot trial. Report of Medical Research Council Working Party on Mild to Moderate Hypertension.

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Abstract

A multicentre pilot trial to assess the feasibility of undertaking a full-scale national trial of treatment for mild to moderate hypertension has been performed and is being continued. By February 1977 over 1800 patients had entered the trial and some have been under observation for three years. The results so far show that the definitive trial is administratively and scientifically feasible and ethically justified.

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Year:  1977        PMID: 324577      PMCID: PMC1607679          DOI: 10.1136/bmj.1.6074.1437

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  3 in total

1.  A SPHYGMOMANOMETER FOR EPIDEMIOLOGISTS.

Authors:  G A ROSE; W W HOLLAND; E A CROWLEY
Journal:  Lancet       Date:  1964-02-08       Impact factor: 79.321

2.  THE ROLE OF BLOOD-PRESSURE CONTROL IN PREVENTING COMPLICATIONS OF HYPERTENSION.

Authors:  M HAMILTON; E M THOMPSON; T K WISNIEWSKI
Journal:  Lancet       Date:  1964-02-01       Impact factor: 79.321

3.  Hypotensive therapy in stroke survivors.

Authors:  A B Carter
Journal:  Lancet       Date:  1970-03-07       Impact factor: 79.321

  3 in total
  18 in total

1.  William Pickles lecture. General practice and the epidemiology of health and disease in families.

Authors:  Graham Watt
Journal:  Br J Gen Pract       Date:  2004-12       Impact factor: 5.386

Review 2.  Experiences from hypertension trials--effects on stroke and coronary heart disease.

Authors:  G Berglund
Journal:  Drugs       Date:  1988       Impact factor: 9.546

3.  The effect of indapamide vs. bendroflumethiazide for primary hypertension: a systematic review.

Authors:  Tatiana V Macfarlane; Filippo Pigazzani; Robert W V Flynn; Thomas M MacDonald
Journal:  Br J Clin Pharmacol       Date:  2018-11-28       Impact factor: 4.335

4.  Diuretics and arrhythmias in the Medical Research Council trial.

Authors:  P K Whelton
Journal:  Drugs       Date:  1984-10       Impact factor: 9.546

Review 5.  Pharmacotherapy for hypertension in adults aged 18 to 59 years.

Authors:  Vijaya M Musini; Francois Gueyffier; Lorri Puil; Douglas M Salzwedel; James M Wright
Journal:  Cochrane Database Syst Rev       Date:  2017-08-16

6.  [Blood pressure during isometric and dynamic exercise under long-term antihypertensive treatment with beta receptor blockaders and diuretics].

Authors:  M Middeke; H Holzgreve
Journal:  Klin Wochenschr       Date:  1983-12-15

Review 7.  Placebo interventions for all clinical conditions.

Authors:  Asbjørn Hróbjartsson; Peter C Gøtzsche
Journal:  Cochrane Database Syst Rev       Date:  2010-01-20

8.  Long acting beta-blockers in the twenty fourth hour.

Authors:  G I Hackett; P Harrison; S Kershaw
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

9.  Reduced peripheral vascular symptoms in elderly patients treated with alpha-methyldopa--a comparison with propranolol.

Authors:  M J VandenBurg; W D Cooper; M L Woollard; W J Currie; C H Bowker
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

10.  Nifedipine in the treatment of hypertension.

Authors:  F Brennan; M Flanagan; S Blake; P Cannon
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

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