Literature DB >> 32454719

Identification, Quantification, and Antioxidant Activity of Hydroalcoholic Extract of Artemisia campestris from Algeria.

Boulanouar Bakchiche1, Abdelaziz Gherib1, Maria Rosário Bronze2, Mosad A Ghareeb3.   

Abstract

OBJECTIVES: Our study aimed to investigate the chemical profile of hydroalcoholic extract of Algerian Artemisia campestris and its antioxidant activity.
MATERIALS AND METHODS: The hydroalcoholic extract of Algerian A. campestris was investigated for its phenolic constituents using high performance liquid chromatography (HPLC)-diode array detection (DAD)-electrospray ionization (ESI)-mass spectrometer (MS)/MS. The in vitro antioxidant activity and total phenolic content were also evaluated via oxygen radical absorbance capacity and Folin-Ciocalteu assays, respectively.
RESULTS: HPLC-DAD-ESI-MS/MS analysis revealed that the main tentatively identified compounds were caffeoylquinic acid isomers, flavonoids, and benzoic acid derivatives. Additionally, the hydroalcoholic extract exhibited a promising antioxidant activity value of 120.5±10.4 μmol Trolox equivalent antioxidant capacity/g dry weight (DW), and a strong correlation exists between this activity and the total phenolic content value of 102.09±1.65 mg/g gallic acid equivalents DW.
CONCLUSION: The hydroalcoholic extract of A. campestris is a promising candidate for the production of naturally occurring antioxidant agents. ©Copyright 2019 Turk J Pharm Sci, Published by Galenos Publishing House.

Entities:  

Keywords:  Artemisia campestris; antioxidant; chlorogenic acid; flavonoids; polyphenols

Year:  2019        PMID: 32454719      PMCID: PMC7227965          DOI: 10.4274/tjps.galenos.2018.99267

Source DB:  PubMed          Journal:  Turk J Pharm Sci        ISSN: 1304-530X


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