Literature DB >> 32452833

Current and potential future applications of human stem cell models in drug development.

Mark Donowitz1,2, Jerrold R Turner3, Alan S Verkman4, Nicholas Constantine Zachos1.   

Abstract

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Year:  2020        PMID： 32452833      PMCID： PMC7324189          DOI： 10.1172/JCI138645

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


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  21 in total

Review 1.  Concordance of the toxicity of pharmaceuticals in humans and in animals.

Authors:  H Olson; G Betton; D Robinson; K Thomas; A Monro; G Kolaja; P Lilly; J Sanders; G Sipes; W Bracken; M Dorato; K Van Deun; P Smith; B Berger; A Heller
Journal:  Regul Toxicol Pharmacol       Date:  2000-08       Impact factor: 3.271

2.  Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Authors:  Toshiro Sato; Robert G Vries; Hugo J Snippert; Marc van de Wetering; Nick Barker; Daniel E Stange; Johan H van Es; Arie Abo; Pekka Kujala; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2009-03-29       Impact factor: 49.962

Review 3.  From 3D cell culture to organs-on-chips.

Authors:  Dongeun Huh; Geraldine A Hamilton; Donald E Ingber
Journal:  Trends Cell Biol       Date:  2011-10-25       Impact factor: 20.808

Review 4.  Primary Cell-Derived Intestinal Models: Recapitulating Physiology.

Authors:  Johanna S Dutton; Samuel S Hinman; Raehyun Kim; Yuli Wang; Nancy L Allbritton
Journal:  Trends Biotechnol       Date:  2018-12-24       Impact factor: 19.536

5.  Identification of stem cells in small intestine and colon by marker gene Lgr5.

Authors:  Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Journal:  Nature       Date:  2007-10-14       Impact factor: 49.962

6.  Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

Authors:  Lawrence Vernetti; Albert Gough; Nicholas Baetz; Sarah Blutt; James R Broughman; Jacquelyn A Brown; Jennifer Foulke-Abel; Nesrin Hasan; Julie In; Edward Kelly; Olga Kovbasnjuk; Jonathan Repper; Nina Senutovitch; Janet Stabb; Catherine Yeung; Nick C Zachos; Mark Donowitz; Mary Estes; Jonathan Himmelfarb; George Truskey; John P Wikswo; D Lansing Taylor
Journal:  Sci Rep       Date:  2017-03-16       Impact factor: 4.379

7.  A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip.

Authors:  Sasan Jalili-Firoozinezhad; Francesca S Gazzaniga; Elizabeth L Calamari; Diogo M Camacho; Cicely W Fadel; Amir Bein; Ben Swenor; Bret Nestor; Michael J Cronce; Alessio Tovaglieri; Oren Levy; Katherine E Gregory; David T Breault; Joaquim M S Cabral; Dennis L Kasper; Richard Novak; Donald E Ingber
Journal:  Nat Biomed Eng       Date:  2019-05-13       Impact factor: 25.671

8.  SARS-CoV-2 productively infects human gut enterocytes.

Authors:  Mart M Lamers; Joep Beumer; Jelte van der Vaart; Bart L Haagmans; Hans Clevers; Kèvin Knoops; Jens Puschhof; Tim I Breugem; Raimond B G Ravelli; J Paul van Schayck; Anna Z Mykytyn; Hans Q Duimel; Elly van Donselaar; Samra Riesebosch; Helma J H Kuijpers; Debby Schipper; Willine J van de Wetering; Miranda de Graaf; Marion Koopmans; Edwin Cuppen; Peter J Peters
Journal:  Science       Date:  2020-05-01       Impact factor: 47.728

Review 9.  Gastrointestinal Organoids: Understanding the Molecular Basis of the Host-Microbe Interface.

Authors:  David R Hill; Jason R Spence
Journal:  Cell Mol Gastroenterol Hepatol       Date:  2016-12-19

10.  Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers.

Authors:  Jianyi Yin; Chung-Ming Tse; Leela Rani Avula; Varsha Singh; Jennifer Foulke-Abel; Hugo R de Jonge; Mark Donowitz
Journal:  Cell Mol Gastroenterol Hepatol       Date:  2018-02-09
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  3 in total

Review 1.  Human Embryo Models and Drug Discovery.

Authors:  Margit Rosner; Manuel Reithofer; Dieter Fink; Markus Hengstschläger
Journal:  Int J Mol Sci       Date:  2021-01-11       Impact factor: 5.923

Review 2.  CRISPR and iPSCs: Recent Developments and Future Perspectives in Neurodegenerative Disease Modelling, Research, and Therapeutics.

Authors:  Tirthankar Sen; Rajkumar P Thummer
Journal:  Neurotox Res       Date:  2022-08-31       Impact factor: 3.978

3.  Evaluation of a Live Attenuated S. sonnei Vaccine Strain in the Human Enteroid Model.

Authors:  Giulia Pilla; Tao Wu; Christen Grassel; Jonathan Moon; Jennifer Foulke-Abel; Christoph M Tang; Eileen M Barry
Journal:  Pathogens       Date:  2021-08-25
  3 in total

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