Literature DB >> 32451908

Prediction of Maternal and Fetal Pharmacokinetics of Dolutegravir and Raltegravir Using Physiologically Based Pharmacokinetic Modeling.

Xiaomei I Liu1, Jeremiah D Momper2, Natella Y Rakhmanina3,4, Dionna J Green5, Gilbert J Burckart6, Tim R Cressey7,8,9, Mark Mirochnick10, Brookie M Best2, John N van den Anker3,11, André Dallmann11,12.   

Abstract

BACKGROUND: Predicting drug pharmacokinetics in pregnant women including placental drug transfer remains challenging. This study aimed to develop and evaluate maternal-fetal physiologically based pharmacokinetic models for two antiretroviral drugs, dolutegravir and raltegravir.

Entities:  

Year:  2020        PMID： 32451908      PMCID： PMC7666002          DOI： 10.1007/s40262-020-00897-9

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN： 0312-5963            Impact factor:   6.447


  74 in total

1.  Prediction of adipose tissue: plasma partition coefficients for structurally unrelated drugs.

Authors:  P Poulin; K Schoenlein; F P Theil
Journal:  J Pharm Sci       Date:  2001-04       Impact factor: 3.534

2.  Effect of low-, moderate-, and high-fat meals on raltegravir pharmacokinetics.

Authors:  Diana M Brainard; Evan J Friedman; Bo Jin; Sheila A Breidinger; Maria D Tillan; Larissa A Wenning; Julie A Stone; Jeffrey A Chodakewitz; John A Wagner; Marian Iwamoto
Journal:  J Clin Pharmacol       Date:  2010-05-10       Impact factor: 3.126

3.  Physiologically based pharmacokinetic modelling 2: predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions.

Authors:  Trudy Rodgers; Malcolm Rowland
Journal:  J Pharm Sci       Date:  2006-06       Impact factor: 3.534

Review 4.  Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy.

Authors:  André Dallmann; Ibrahim Ince; Michaela Meyer; Stefan Willmann; Thomas Eissing; Georg Hempel
Journal:  Clin Pharmacokinet       Date:  2017-11       Impact factor: 6.447

5.  Estimated Perinatal HIV Infection Among Infants Born in the United States, 2002-2013.

Authors:  Allan W Taylor; Steven R Nesheim; Xinjian Zhang; Ruiguang Song; Lauren F FitzHarris; Margaret A Lampe; Paul J Weidle; Patricia Sweeney
Journal:  JAMA Pediatr       Date:  2017-05-01       Impact factor: 16.193

6.  Reconsidering the Number of Women With HIV Infection Who Give Birth Annually in the United States.

Authors:  Steven R Nesheim; Lauren F FitzHarris; Margaret A Lampe; Kristen Mahle Gray
Journal:  Public Health Rep       Date:  2018-09-28       Impact factor: 2.792

Review 7.  The significance of plasma protein binding on the fetal/maternal distribution of drugs at steady-state.

Authors:  M D Hill; F P Abramson
Journal:  Clin Pharmacokinet       Date:  1988-03       Impact factor: 6.447

8.  Pharmacokinetics and safety of S/GSK1349572, a next-generation HIV integrase inhibitor, in healthy volunteers.

Authors:  Sherene Min; Ivy Song; Julie Borland; Shuguang Chen; Yu Lou; Tamio Fujiwara; Stephen C Piscitelli
Journal:  Antimicrob Agents Chemother       Date:  2009-11-02       Impact factor: 5.191

9.  The prenatal and postnatal development of UDP-glucuronyltransferase activity towards bilirubin and the effect of premature birth on this activity in the human liver.

Authors:  N Kawade; S Onishi
Journal:  Biochem J       Date:  1981-04-15       Impact factor: 3.857

10.  Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line.

Authors:  Afraa Zrieki; Robert Farinotti; Marion Buyse
Journal:  Pharm Res       Date:  2008-06-26       Impact factor: 4.580
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  2 in total

1.  Physiologically Based Pharmacokinetic Modeling Framework to Predict Neonatal Pharmacokinetics of Transplacentally Acquired Emtricitabine, Dolutegravir, and Raltegravir.

Authors:  Xiaomei I Liu; Jeremiah D Momper; Natella Y Rakhmanina; Dionna J Green; Gilbert J Burckart; Tim R Cressey; Mark Mirochnick; Brookie M Best; John N van den Anker; André Dallmann
Journal:  Clin Pharmacokinet       Date:  2021-02-02       Impact factor: 5.577

2.  Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Development.

Authors:  Sherry Zhao; Mary Gockenbach; Manuela Grimstein; Hari Cheryl Sachs; Mark Mirochnick; Kimberly Struble; Yodit Belew; Jian Wang; Edmund V Capparelli; Brookie M Best; Tamara Johnson; Jeremiah D Momper; Anil R Maharaj
Journal:  Front Pediatr       Date:  2021-10-13       Impact factor: 3.569
  2 in total

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