Literature DB >> 32450151

Beyond Stiffness: Collagen Signaling in Pancreatic Cancer and Pancreas Regeneration.

Huocong Huang1, Rolf A Brekken2.   

Abstract

This commentary highlights the article by Ruggeri et al that reports the importance of discoidin domain receptor 1 in tissue homeostasis in pancreatic injury and pancreatic ductal adenocarcinoma pathogenesis.
Copyright © 2020 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

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Year:  2020        PMID： 32450151      PMCID： PMC7397458          DOI： 10.1016/j.ajpath.2020.05.005

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


  26 in total

1.  Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.

Authors:  Berna C Özdemir; Tsvetelina Pentcheva-Hoang; Julienne L Carstens; Xiaofeng Zheng; Chia-Chin Wu; Tyler R Simpson; Hanane Laklai; Hikaru Sugimoto; Christoph Kahlert; Sergey V Novitskiy; Ana De Jesus-Acosta; Padmanee Sharma; Pedram Heidari; Umar Mahmood; Lynda Chin; Harold L Moses; Valerie M Weaver; Anirban Maitra; James P Allison; Valerie S LeBleu; Raghu Kalluri
Journal:  Cancer Cell       Date:  2014-05-22       Impact factor: 31.743

2.  Single-Cell Analysis Uncovers Clonal Acinar Cell Heterogeneity in the Adult Pancreas.

Authors:  Damian Wollny; Sheng Zhao; Isabelle Everlien; Xiaokang Lun; Jan Brunken; Daniel Brüne; Frederik Ziebell; Inna Tabansky; Wilko Weichert; Anna Marciniak-Czochra; Ana Martin-Villalba
Journal:  Dev Cell       Date:  2016-10-27       Impact factor: 12.270

3.  Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma.

Authors:  Paolo P Provenzano; Carlos Cuevas; Amy E Chang; Vikas K Goel; Daniel D Von Hoff; Sunil R Hingorani
Journal:  Cancer Cell       Date:  2012-03-20       Impact factor: 31.743

4.  Up-regulation of N-cadherin by Collagen I-activated Discoidin Domain Receptor 1 in Pancreatic Cancer Requires the Adaptor Molecule Shc1.

Authors:  Huocong Huang; Robert A Svoboda; Audrey J Lazenby; Jintana Saowapa; Nina Chaika; Ke Ding; Margaret J Wheelock; Keith R Johnson
Journal:  J Biol Chem       Date:  2016-09-07       Impact factor: 5.157

5.  Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.

Authors:  Chiara Ambrogio; Gonzalo Gómez-López; Mattia Falcone; August Vidal; Ernest Nadal; Nicola Crosetto; Rafael B Blasco; Pablo J Fernández-Marcos; Montserrat Sánchez-Céspedes; Xiaomei Ren; Zhen Wang; Ke Ding; Manuel Hidalgo; Manuel Serrano; Alberto Villanueva; David Santamaría; Mariano Barbacid
Journal:  Nat Med       Date:  2016-02-08       Impact factor: 53.440

Review 6.  Getting a grip on adhesion: Cadherin switching and collagen signaling.

Authors:  Huocong Huang; Steven Wright; Junqiu Zhang; Rolf A Brekken
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2019-04-05       Impact factor: 4.739

7.  Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development.

Authors:  W F Vogel; A Aszódi; F Alves; T Pawson
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

8.  Identification of cancer genes that are independent of dominant proliferation and lineage programs.

Authors:  Laura M Selfors; Daniel G Stover; Isaac S Harris; Joan S Brugge; Jonathan L Coloff
Journal:  Proc Natl Acad Sci U S A       Date:  2017-12-11       Impact factor: 11.205

9.  Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma.

Authors:  Robert J Torphy; Zhen Wang; Aisha True-Yasaki; Keith E Volmar; Naim Rashid; Benjamin Yeh; Judy M Anderson; Julia S Johansen; Michael A Hollingsworth; Jen Jen Yeh; Eric A Collisson
Journal:  JCO Precis Oncol       Date:  2018-01-16

10.  Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers.

Authors:  Ken Takai; Allison P Drain; Devon A Lawson; Laurie E Littlepage; Marcela Karpuj; Kai Kessenbrock; Annie Le; Kenichi Inoue; Valerie M Weaver; Zena Werb
Journal:  Genes Dev       Date:  2018-02-26       Impact factor: 11.361
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