| Literature DB >> 324482 |
Abstract
The immunochemical specificity of the immunofluorescent Crithidia luciliae method for detection of antibodies to double-stranded DNA (dsDNA) was confirmed by demonstrating abolition of staining by DNase digestion and by absorption with dsDNA. This method was less sensitive than a Millipore filter method for detecting antibodies to DNA. It was positive only in subjects with systemic lupus erythematosus or drug-induced antinuclear factors. This technique appears suitable for study of the immunochemical characteristics fo antibodies to dsDNA.Entities:
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Year: 1977 PMID: 324482 DOI: 10.1002/art.1780200308
Source DB: PubMed Journal: Arthritis Rheum ISSN: 0004-3591