Literature DB >> 32446812

Induced-membrane treatment of refractory humeral non-union with or without bone defect.

Julien Gaillard1, Alain-Charles Masquelet2, Pierre Boutroux2, Adeline Cambon-Binder2.   

Abstract

INTRODUCTION: Treatment of humeral non-union with or without bone defect is complex, with non-negligible rates of complication and failure. Few reports focused on management of treatment failure.
OBJECTIVE: The study hypothesis was that the induced-membrane technique associated in a 2-stage strategy to internal fixation provides systematic bone healing in refractory humeral non-union.
MATERIAL AND METHODS: The study included 15 patients, with a median age of 46.6 years, with humeral non-union of a mean 24 months' progression and mean history of 3 attempted revision surgeries. Seven patients showed bone defect, exceeding 5cm in 2 cases. Six had history of radial palsy.
RESULTS: Consolidation was achieved in all cases, at a mean 4.6 months. Ten patients underwent radial nerve transposition, 6 of whom had shown radial motor nerve palsy; all recovered within 2 to 5 months. There was 1 case of superficial infection, and 1 of seroma. DISCUSSION: The induced-membrane technique ensures bone healing due to the biological properties of the membrane; the main drawback is the need for 2-stage surgery. When bone defect exceeds 5cm, a multi-perforated fibula segment can be placed inside the membrane to increase primary stability and enhance bone integration.
CONCLUSION: The induced-membrane technique is suited to humeral non-union, with or without bone defect. The 2-stage strategy is mandatory in case of suspected latent infection. In the 2-stage procedure, anteromedial radial nerve transposition facilitates the bone-graft stage. LEVEL OF EVIDENCE: IV, retrospective study.
Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Humeral non-union; Induced membrane; Masquelet technique; Radial nerve transposition

Mesh:

Year:  2020        PMID: 32446812     DOI: 10.1016/j.otsr.2020.02.015

Source DB:  PubMed          Journal:  Orthop Traumatol Surg Res        ISSN: 1877-0568            Impact factor:   2.256


  4 in total

1.  Management of segmental bone defects of the upper limb: a scoping review with data synthesis to inform decision making.

Authors:  Nando Ferreira; Aaron Kumar Saini; Franz Friedrich Birkholtz; Maritz Laubscher
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-03-06

2.  Bridge plating with decortication, autologous bone graft, and tight closure: a "stepwise surgical diamond concept" for treatment of nonunion in a series of fifty five patients.

Authors:  Ali Hassan Chamseddine; Mark E Mouchantaf; Kinan F Freiha; Ali H Asfour; Abbas A Dib; Hassan M Wardani; Ali M Bazzal; Georgio E Nahed
Journal:  Int Orthop       Date:  2022-03-20       Impact factor: 3.479

3.  Novel application of 3D printed microporous prosthesis to repair humeral nonunion with segmental bone defects: a case report.

Authors:  Weipeng Qiu; Bingchuan Liu; Xingcai Li; Yun Tian
Journal:  Ann Transl Med       Date:  2022-08

Review 4.  Masquelet technique in military practice: specificities and future directions for combat-related bone defect reconstruction.

Authors:  Laurent Mathieu; Romain Mourtialon; Marjorie Durand; Arnaud de Rousiers; Nicolas de l'Escalopier; Jean-Marc Collombet
Journal:  Mil Med Res       Date:  2022-09-02
  4 in total

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