Linda S Franck1, Renée A Shellhaas2, Monica Lemmon3, Julie Sturza2, Janet S Soul4, Taeun Chang5, Courtney J Wusthoff6, Catherine J Chu7, Shavonne L Massey8, Nicholas S Abend9, Cameron Thomas10, Elizabeth E Rogers11, Charles E McCulloch12, Katie Grant13, Lisa Grossbauer14, Kamil Pawlowski15, Hannah C Glass16. 1. Department of Family Health Care Nursing, University of California San Francisco, San Francisco, CA. Electronic address: linda.franck@ucsf.edu. 2. Department of Pediatrics, University of Michigan, Ann Arbor, MI. 3. Division of Pediatric Neurology and Developmental Medicine, Department of Pediatrics, Duke University School of Medicine, Durham, NC. 4. Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA. 5. Department of Neurology, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC. 6. Departments of Neurology and Pediatrics, Stanford University, Palo Alto, CA. 7. Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA. 8. Departments of Neurology and Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. 9. Departments of Neurology and Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Departments of Anesthesia and Critical Care Medicine, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. 10. Department of Pediatrics, University of Cincinnati, Cincinnati, OH; Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. 11. Department of Pediatrics, UCSF Benioff Children's Hospital, University of California San Francisco, San Francisco, CA. 12. Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA. 13. NSR Parent Partner, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. 14. NSR Parent Partner, Children's Hospital of Philadelphia, Philadelphia, PA. 15. NSR Parent Partner, UCSF Benioff Children's Hospital, San Francisco, CA. 16. Departments of Neurology and Pediatrics, UCSF Benioff Children's Hospital, University of California San Francisco, San Francisco, CA.
Abstract
OBJECTIVE: To characterize and determine risk factors for key dimensions of well-being at hospital discharge in families of neonates with acute symptomatic seizures. STUDY DESIGN: This prospective, observational cohort study enrolled 144 parent-infant dyads among neonates with acute symptomatic seizures from 9 pediatric hospitals in the Neonatal Seizure Registry. One parent per family completed a discharge survey, which included measures of anxiety and depression, health-related quality of life, and impact on the family. Multivariable regression analyses adjusted for site were constructed to examine parent and infant characteristics associated with well-being. RESULTS: At discharge, 54% of parents reported symptoms of anxiety and 32% reported symptoms of depression. Parents of infants with hypoxic-ischemic encephalopathy reported more depression and worse quality of life than parents of infants with other seizure etiologies. Parental quality of life was also lower with greater infant age at discharge. A higher level of maternal education was associated with greater impact on the family. All these differences were medium to large effect sizes, ranging from 0.52 to 0.78. CONCLUSIONS: Symptoms of anxiety and depression are common in parents of infants with neonatal seizures, and several parent and infant characteristics are associated with poorer parental quality of life and family well-being. These findings are a call to action to improve mental health screening and services for parents of infants with neonatal seizures.
OBJECTIVE: To characterize and determine risk factors for key dimensions of well-being at hospital discharge in families of neonates with acute symptomatic seizures. STUDY DESIGN: This prospective, observational cohort study enrolled 144 parent-infant dyads among neonates with acute symptomatic seizures from 9 pediatric hospitals in the Neonatal Seizure Registry. One parent per family completed a discharge survey, which included measures of anxiety and depression, health-related quality of life, and impact on the family. Multivariable regression analyses adjusted for site were constructed to examine parent and infant characteristics associated with well-being. RESULTS: At discharge, 54% of parents reported symptoms of anxiety and 32% reported symptoms of depression. Parents of infants with hypoxic-ischemic encephalopathy reported more depression and worse quality of life than parents of infants with other seizure etiologies. Parental quality of life was also lower with greater infant age at discharge. A higher level of maternal education was associated with greater impact on the family. All these differences were medium to large effect sizes, ranging from 0.52 to 0.78. CONCLUSIONS: Symptoms of anxiety and depression are common in parents of infants with neonatal seizures, and several parent and infant characteristics are associated with poorer parental quality of life and family well-being. These findings are a call to action to improve mental health screening and services for parents of infants with neonatal seizures.
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Authors: Mary C Barks; Emma A Schindler; Peter A Ubel; Megan G Jiao; Kathryn I Pollak; Hanna E Huffstetler; Monica E Lemmon Journal: Patient Educ Couns Date: 2021-06-11
Authors: Monica E Lemmon; Hannah C Glass; Renée A Shellhaas; Mary Carol Barks; Simran Bansal; Dana Annis; Jennifer L Guerriero; Betsy Pilon; Courtney J Wusthoff; Taeun Chang; Janet S Soul; Catherine J Chu; Cameron Thomas; Shavonne L Massey; Nicholas S Abend; Stephanie Rau; Elizabeth E Rogers; Linda S Franck Journal: Pediatr Neurol Date: 2021-07-30 Impact factor: 3.372
Authors: Reem Malouf; Sian Harrison; Hollie A L Burton; Chris Gale; Alan Stein; Linda S Franck; Fiona Alderdice Journal: EClinicalMedicine Date: 2021-12-21
Authors: Linda S Franck; Renée A Shellhaas; Monica E Lemmon; Julie Sturza; Marty Barnes; Trisha Brogi; Elizabeth Hill; Katrina Moline; Janet S Soul; Taeun Chang; Courtney J Wusthoff; Catherine J Chu; Shavonne L Massey; Nicholas S Abend; Cameron Thomas; Elizabeth E Rogers; Charles E McCulloch; Hannah C Glass Journal: Children (Basel) Date: 2021-12-22