Literature DB >> 32445077

Outcomes of ketorolac versus depomedrol infiltrations for subacromial impingement syndrome: a randomized controlled trial.

T Goyal1, S Paul1, S S Sethy2, A K Choudhury1.   

Abstract

PURPOSE: Local subacromial infiltration with steroids is a common method of treatment of subacromial impingement syndrome. However, the use of steroids has concerns like tendon rupture, articular cartilage changes and infections. Local NSAIDs infiltration has recently been tried in literature. This study compares the effect of subacromial injections of ketorolac with steroids.
METHODS: A randomized controlled study was planned with 35 patients in each group. Patients in group-1 were infiltrated with subacromial ketorolac (60 mg with 2% lignocaine) and in group-2 with a steroid (methylprednisolone-40 mg with 2% lignocaine). A similar rehabilitation protocol was followed, and clinical outcomes were analyzed using visual analog scale (VAS) for pain and shoulder pain and disability score (SPADI) and range of motion at one-month and three-months follow-up.
RESULTS: Total data of 67 patients were analyzed, as three patients were lost to follow-up. In group 1, mean VAS improved from 7.9 [Formula: see text] 0.95 to 3.19 [Formula: see text] 0.81 (p < 0.001) and SPADI improved from 61.41 [Formula: see text] 11.86 to 28.91 [Formula: see text] 9.06 (p < 0.001) at three months, respectively. In group 2, mean VAS improved from 8.05 [Formula: see text] 0.94 to 2.9 [Formula: see text] 0.64 (p < 0.001) and SPADI improved from 63.45 [Formula: see text] 9.64 to 25.32 [Formula: see text] 6.87 (p < 0.001) at three months, respectively. However, there were no differences in functional outcomes between the groups (p = 0.21 for VAS, p = 0.16 for SPADI).
CONCLUSION: Subacromial ketorolac infiltration has an equivalent outcome as that of steroid infiltration. Ketorolac could be considered as a reasonable alternative to steroids in cases where it is contraindicated.
© 2020. Istituto Ortopedico Rizzoli.

Entities:  

Keywords:  Ketorolac; Nonsteroidal anti-inflammatory drugs; Shoulder pain; Steroid injections; Subacromial impingement; Subacromial injection

Mesh:

Substances:

Year:  2020        PMID: 32445077     DOI: 10.1007/s12306-020-00667-7

Source DB:  PubMed          Journal:  Musculoskelet Surg        ISSN: 2035-5114


  5 in total

1.  Corticosteroid injections in adhesive capsulitis: investigation of their value and site.

Authors:  T E Rizk; R S Pinals; A S Talaiver
Journal:  Arch Phys Med Rehabil       Date:  1991-01       Impact factor: 3.966

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3.  A prospective double blind dummy placebo controlled study comparing triamcinolone hexacetonide injection with oral diclofenac 50 mg TDS in patients with rotator cuff tendinitis.

Authors:  A O Adebajo; P Nash; B L Hazleman
Journal:  J Rheumatol       Date:  1990-09       Impact factor: 4.666

4.  Efficacy and Safety of Subacromial Corticosteroid Injection in Type 2 Diabetic Patients.

Authors:  Davide Blonna; Davide Edoardo Bonasia; Lorenzo Mattei; Enrico Bellato; Valentina Greco; Roberto Rossi
Journal:  Pain Res Treat       Date:  2018-09-20

Review 5.  The Effect of Intra-articular Corticosteroids on Articular Cartilage: A Systematic Review.

Authors:  Chloe Wernecke; Hillary J Braun; Jason L Dragoo
Journal:  Orthop J Sports Med       Date:  2015-04-27
  5 in total
  1 in total

1.  The effects of a single-dose subacromial injection of a nonsteroidal anti-inflammatory drug in geriatric patients with subacromial impingement syndrome: a randomized double-blind study.

Authors:  Young Bae Kim; Woo-Seung Lee; Jun-Sung Won
Journal:  Clin Shoulder Elb       Date:  2021-03-02
  1 in total

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