Ali Seifi1, John Vincent Lacci2, Daniel Agustin Godoy3. 1. Department of Neurosurgery, University of Texas Health at San Antonio, San Antonio, TX 78229, United States. Electronic address: seifi@uthscsa.edu. 2. University of Texas Health at San Antonio, San Antonio, TX, Mail Code 7843, 7703 Floyd Curl Drive United States. Electronic address: johnlacci@gmail.com. 3. Neurointensive Care Unit, Sanatorio Pasteur, Intensive Care Unit, Hospital San Juan Bautista, Chacabuco 675, 2nd Floor, Catamarca, Argentina. Electronic address: dagodoytorres@yahoo.com.ar.
Abstract
OBJECTIVES: The epidemiological analysis of brain death (BD) can assist physicians in their development of relevant guidelines regarding training and action protocols. This study aims to find the incidence of BD in the United States. PATIENTS AND METHODS: This is a cross-sectional study between 2012 and 2016 in the United States. BD data were extracted from the Healthcare Cost and Utilization Project (HCUP) and compared with those of all in-hospital Cardio-Pulmonary Deaths (ih-CPD). RESULTS: There were 69,735 BD (0.039%) and 3,309,955 ih-CPD (1.85%) with one BD for every fifty ih-CPD. The number of BD increased from 12,575 in 2012 to 15,405 in 2016 (p < 0.0001), with an average of 39 BD per 100,000 discharges and a mean age of 47.83 ± 20.93 years old. Both groups were mainly male and ethnically white; however blacks had the highest rate of BD per capita (p < 0.0001). The most frequently reported cause for BD was the Central Nervous System diseases (50.17%). CONCLUSIONS: In recent years, the incidence of BD has increased in the United States. Knowing the incidence of BD and the establishment of long-term programs that raise awareness about BD may increase the number of potential organ donors in the future.
OBJECTIVES: The epidemiological analysis of brain death (BD) can assist physicians in their development of relevant guidelines regarding training and action protocols. This study aims to find the incidence of BD in the United States. PATIENTS AND METHODS: This is a cross-sectional study between 2012 and 2016 in the United States. BD data were extracted from the Healthcare Cost and Utilization Project (HCUP) and compared with those of all in-hospital Cardio-Pulmonary Deaths (ih-CPD). RESULTS: There were 69,735 BD (0.039%) and 3,309,955 ih-CPD (1.85%) with one BD for every fifty ih-CPD. The number of BD increased from 12,575 in 2012 to 15,405 in 2016 (p < 0.0001), with an average of 39 BD per 100,000 discharges and a mean age of 47.83 ± 20.93 years old. Both groups were mainly male and ethnically white; however blacks had the highest rate of BD per capita (p < 0.0001). The most frequently reported cause for BD was the Central Nervous System diseases (50.17%). CONCLUSIONS: In recent years, the incidence of BD has increased in the United States. Knowing the incidence of BD and the establishment of long-term programs that raise awareness about BD may increase the number of potential organ donors in the future.