Literature DB >> 32441682

Hazardous Drug Exposure: Case Report Analysis From a Prospective, Multisite Study of Oncology Nurses' Exposure in Ambulatory Settings.

Christopher R Friese1, Mandy Wong2, Alex Fauer3, Kari Mendelsohn-Victor3, Martha Polovich4, Marjorie C McCullagh3.   

Abstract

BACKGROUND: Hazardous drug exposure is an occupational health hazard to oncology nurses. Sparse data are available regarding the frequency and characteristics of hazardous drug spills.
OBJECTIVES: This article aims to describe nurses' hazardous drug exposures and use of personal protective equipment during drug spills.
METHODS: The Drug Exposure Feedback and Education for Nurses' Safety study launched in March 2015. When drug spills occurred, consented RNs administering chemotherapy in ambulatory infusion settings completed brief questionnaires. Descriptive statistics were used to summarize equipment use and spill events.
FINDINGS: Spills were common, despite the use of closed-system transfer devices. Over two years, 51 nurses from 12 participating academic infusion centers reported 61 unique spills. Spills commonly involved highly toxic drugs. Personal protective equipment use during drug spills was suboptimal. These foundational data reveal gaps in clinical practice.

Entities:  

Keywords:  administration; ambulatory; hazardous drugs; occupational health; oncology

Mesh:

Substances:

Year:  2020        PMID: 32441682      PMCID: PMC7271974          DOI: 10.1188/20.CJON.249-255

Source DB:  PubMed          Journal:  Clin J Oncol Nurs        ISSN: 1092-1095            Impact factor:   1.027


  11 in total

1.  Nurses' use of hazardous drug-handling precautions and awareness of national safety guidelines.

Authors:  Martha Polovich; Susan Martin
Journal:  Oncol Nurs Forum       Date:  2011-11       Impact factor: 2.172

2.  Summary of the Workshop on the Safe Handling of Hazardous Drugs Cohosted by the National Institute for Occupational Safety and Health and the American Society of Clinical Oncology.

Authors:  Thomas H Connor; Paul Celano; James N Frame; Robin T Zon
Journal:  J Oncol Pract       Date:  2017-02-21       Impact factor: 3.840

3.  Randomized Controlled Trial of an Intervention to Improve Nurses' Hazardous Drug Handling

Authors:  Christopher R Friese; James Yang; Kari Mendelsohn-Victor; Marjorie McCullagh
Journal:  Oncol Nurs Forum       Date:  2019-03-01       Impact factor: 2.172

4.  Personal Protective Equipment Use and Hazardous Drug Spills Among Ambulatory Oncology Nurses

Authors:  Bei He; Kari Mendelsohn-Victor; Marjorie McCullagh; Christopher Friese
Journal:  Oncol Nurs Forum       Date:  2017-01-06       Impact factor: 2.172

Review 5.  Preventable exposures associated with human cancers.

Authors:  Vincent James Cogliano; Robert Baan; Kurt Straif; Yann Grosse; Béatrice Lauby-Secretan; Fatiha El Ghissassi; Véronique Bouvard; Lamia Benbrahim-Tallaa; Neela Guha; Crystal Freeman; Laurent Galichet; Christopher P Wild
Journal:  J Natl Cancer Inst       Date:  2011-12-12       Impact factor: 13.506

Review 6.  Preventing occupational exposures to antineoplastic drugs in health care settings.

Authors:  Thomas H Connor; Melissa A McDiarmid
Journal:  CA Cancer J Clin       Date:  2006 Nov-Dec       Impact factor: 508.702

7.  Registry-Based Prospective, Active Surveillance of Medical-Device Safety.

Authors:  Frederic S Resnic; Arjun Majithia; Danica Marinac-Dabic; Susan Robbins; Henry Ssemaganda; Kathleen Hewitt; Angelo Ponirakis; Nilsa Loyo-Berrios; Issam Moussa; Joseph Drozda; Sharon-Lise Normand; Michael E Matheny
Journal:  N Engl J Med       Date:  2017-01-25       Impact factor: 91.245

8.  Antineoplastic drug exposure in an ambulatory setting: a pilot study.

Authors:  Christopher R Friese; Cristin McArdle; Ting Zhao; Duxin Sun; Ivan Spasojevic; Martha Polovich; Marjorie C McCullagh
Journal:  Cancer Nurs       Date:  2015 Mar-Apr       Impact factor: 2.592

9.  CE: Original Research: Antineoplastic Drug Administration by Pregnant and Nonpregnant Nurses: An Exploration of the Use of Protective Gloves and Gowns.

Authors:  Christina C Lawson; Candice Y Johnson; Feiby L Nassan; Thomas H Connor; James M Boiano; Carissa M Rocheleau; Jorge E Chavarro; Janet W Rich-Edwards
Journal:  Am J Nurs       Date:  2019-01       Impact factor: 2.220

10.  DEFENS - Drug Exposure Feedback and Education for Nurses' Safety: study protocol for a randomized controlled trial.

Authors:  Christopher R Friese; Kari Mendelsohn-Victor; Bo Wen; Duxin Sun; Kathleen Sutcliffe; James J Yang; David L Ronis; Marjorie C McCullagh
Journal:  Trials       Date:  2015-04-17       Impact factor: 2.279

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