Literature DB >> 32441673

Adrenal Insufficiency: Immune Checkpoint Inhibitors and Immune-Related Adverse Event Management.

Kiera B Hobbs1, Susan Yackzan2.   

Abstract

Adrenal insufficiency (AI) is a potential immune-related adverse event (irAE) of immunotherapy (e.g., checkpoint inhibitor). If not identified and treated promptly, AI can be life-threatening. Unlike other irAEs, AI may be irreversible, requiring long-term glucocorticoid and mineralocorticoid replacement. Provider and patient education are essential in the management of immune checkpoint inhibitor-induced AI.

Entities:  

Keywords:  adrenal insufficiency; immune checkpoint inhibitor; immune-related adverse event

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Year:  2020        PMID: 32441673     DOI: 10.1188/20.CJON.240-243

Source DB:  PubMed          Journal:  Clin J Oncol Nurs        ISSN: 1092-1095            Impact factor:   1.027


  2 in total

1.  Immune-Related Adverse Events Associated With Outcomes in Patients With NSCLC Treated With Anti-PD-1 Inhibitors: A Systematic Review and Meta-Analysis.

Authors:  Zhe Zhao; Xinfeng Wang; Jinghan Qu; Wei Zuo; Yan Tang; Huijuan Zhu; Xiaoguang Chen
Journal:  Front Oncol       Date:  2021-09-15       Impact factor: 6.244

2.  Immune checkpoint inhibitors and adrenal insufficiency: a large-sample case series study.

Authors:  Kai Cui; Ziqi Wang; Qianqian Zhang; Xiaoju Zhang
Journal:  Ann Transl Med       Date:  2022-03
  2 in total

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