Antibiotics in aquatic environments of China: A review and meta-analysis.

Antibiotics have adverse effects on human health and aquatic ecosystems in water environment, which is the main pool. In this study, antibiotics in the aquatic environment of China, containing both surface water and groundwater, were first systematically reviewed. That is essential for surface water and groundwater guideline and industry management. 128 articles were reviewed, containing 116 papers on surface water and 12 papers on groundwater. 94 antibiotics were detected at least once in the aquatic environment of China and most of the studies were in the eastern areas of China. The median concentrations of most antibiotics were below than 100 ng/L in the surface water and 10 ng/L in the groundwater. The concentrations of most antibiotics in China were similar or a little higher than in other countries. According to risk assessment, three antibiotics (enrofloxacin, ofloxacin and erythromycin) and three regions (Haihe River, Wangyang River and Taihu Lake) should be given more concerns. Strengthened policy and management are needed in these regions. In the future, more studies on groundwater and a priority list of antibiotics in the aquatic environment was needed.