Literature DB >> 32434987

Genetic and environmental factors underlying keratinocyte carcinoma risk.

Hélène Choquet1, Sepideh Ashrafzadeh2,3, Yuhree Kim2,3, Maryam M Asgari2,3, Eric Jorgenson1.   

Abstract

Recent large-scale GWAS and large epidemiologic studies have accelerated the discovery of genes and environmental factors that contribute to the risk of keratinocyte carcinoma (KC), which includes basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). This Review summarizes the genomic regions associated with SCC and BCC risk, examines the genetic overlap between SCC and BCC, and discusses biological pathways involved in SCC and BCC development. Next, we review environmental factors that are associated with KC risk, including those that are shared between SCC and BCC as well as others that associated with only one type of KC. We conclude with a critical appraisal of current research and potential directions for future research.

Entities:  

Mesh：

Year:  2020        PMID： 32434987      PMCID： PMC7259534          DOI： 10.1172/jci.insight.134783

Source DB:  PubMed          Journal:  JCI Insight        ISSN： 2379-3708


  121 in total

1.  A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention.

Authors:  Andrew C Chen; Andrew J Martin; Bonita Choy; Pablo Fernández-Peñas; Robyn A Dalziell; Catriona A McKenzie; Richard A Scolyer; Haryana M Dhillon; Janette L Vardy; Anne Kricker; Gayathri St George; Niranthari Chinniah; Gary M Halliday; Diona L Damian
Journal:  N Engl J Med       Date:  2015-10-22       Impact factor: 91.245

2.  Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1.

Authors:  David R Goudie; Mariella D'Alessandro; Barry Merriman; Hane Lee; Ildikó Szeverényi; Stuart Avery; Brian D O'Connor; Stanley F Nelson; Stephanie E Coats; Arlene Stewart; Lesley Christie; Gabriella Pichert; Jean Friedel; Ian Hayes; Nigel Burrows; Sean Whittaker; Anne-Marie Gerdes; Sigurd Broesby-Olsen; Malcolm A Ferguson-Smith; Chandra Verma; Declan P Lunny; Bruno Reversade; E Birgitte Lane
Journal:  Nat Genet       Date:  2011-02-27       Impact factor: 38.330

3.  Familial Risk and Heritability of Cancer Among Twins in Nordic Countries.

Authors:  Lorelei A Mucci; Jacob B Hjelmborg; Jennifer R Harris; Kamila Czene; David J Havelick; Thomas Scheike; Rebecca E Graff; Klaus Holst; Sören Möller; Robert H Unger; Christina McIntosh; Elizabeth Nuttall; Ingunn Brandt; Kathryn L Penney; Mikael Hartman; Peter Kraft; Giovanni Parmigiani; Kaare Christensen; Markku Koskenvuo; Niels V Holm; Kauko Heikkilä; Eero Pukkala; Axel Skytthe; Hans-Olov Adami; Jaakko Kaprio
Journal:  JAMA       Date:  2016-01-05       Impact factor: 56.272

4.  Effect of retinol in preventing squamous cell skin cancer in moderate-risk subjects: a randomized, double-blind, controlled trial. Southwest Skin Cancer Prevention Study Group.

Authors:  T E Moon; N Levine; B Cartmel; J L Bangert; S Rodney; Q Dong; Y M Peng; D S Alberts
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  1997-11       Impact factor: 4.254

5.  Alcohol intake and early-onset basal cell carcinoma in a case-control study.

Authors:  Y Zhang; L M Ferrucci; B Cartmel; A M Molinaro; D J Leffell; A E Bale; S T Mayne
Journal:  Br J Dermatol       Date:  2014-11-20       Impact factor: 9.302

6.  Solid cancer incidence in atomic bomb survivors: 1958-1998.

Authors:  D L Preston; E Ron; S Tokuoka; S Funamoto; N Nishi; M Soda; K Mabuchi; K Kodama
Journal:  Radiat Res       Date:  2007-07       Impact factor: 2.841

7.  Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole.

Authors:  Edward W Cowen; Josephine C Nguyen; Daniel D Miller; Diana McShane; Sarah T Arron; Neil S Prose; Maria L Turner; Lindy P Fox
Journal:  J Am Acad Dermatol       Date:  2009-11-06       Impact factor: 11.527

8.  Cutting Edge: Foxp1 Controls Naive CD8+ T Cell Quiescence by Simultaneously Repressing Key Pathways in Cellular Metabolism and Cell Cycle Progression.

Authors:  Hairong Wei; Jianlin Geng; Bi Shi; Zhenghui Liu; Yin-Hu Wang; Anna C Stevens; Stephanie L Sprout; Min Yao; Haikun Wang; Hui Hu
Journal:  J Immunol       Date:  2016-03-21       Impact factor: 5.422

9.  Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.

Authors:  Simon N Stacey; Patrick Sulem; Daniel F Gudbjartsson; Aslaug Jonasdottir; Gudmar Thorleifsson; Sigurjon A Gudjonsson; Gisli Masson; Julius Gudmundsson; Bardur Sigurgeirsson; Kristrun R Benediktsdottir; Kristin Thorisdottir; Rafn Ragnarsson; Victoria Fuentelsaz; Cristina Corredera; Matilde Grasa; Dolores Planelles; Onofre Sanmartin; Peter Rudnai; Eugene Gurzau; Kvetoslava Koppova; Kari Hemminki; Bjørn A Nexø; Anne Tjønneland; Kim Overvad; Hrefna Johannsdottir; Hafdis T Helgadottir; Unnur Thorsteinsdottir; Augustine Kong; Ulla Vogel; Rajiv Kumar; Eduardo Nagore; José I Mayordomo; Thorunn Rafnar; Jon H Olafsson; Kari Stefansson
Journal:  Hum Mol Genet       Date:  2014-01-08       Impact factor: 5.121

10.  Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma.

Authors:  Nilah M Ioannidis; Wei Wang; Nicholas A Furlotte; David A Hinds; Carlos D Bustamante; Eric Jorgenson; Maryam M Asgari; Alice S Whittemore
Journal:  Nat Commun       Date:  2018-10-15       Impact factor: 17.694
View more
  6 in total

1.  Synchronous Basal Cell Carcinoma and Squamous Cell Carcinoma of Nasal Vestibule With Novel Unique Variants Identified by Whole-exome Sequencing.

Authors:  Ida Ghlichloo; Zhongbo Jin; Ruohao Fan; Caili Tong; Petr Starostik; Jeremy R Chien; Jinping Lai
Journal:  In Vivo       Date:  2022 Jan-Feb       Impact factor: 2.155

Review 2.  Basal Cell Carcinoma and Hedgehog Pathway Inhibitors: Focus on Immune Response.

Authors:  Donatella Gambini; Emanuela Passoni; Gianluca Nazzaro; Giada Beltramini; Gianluca Tomasello; Michele Ghidini; Elisabetta Kuhn; Ornella Garrone
Journal:  Front Med (Lausanne)       Date:  2022-06-14

3.  Assessment of the Predictive Value of Spectrophotometric Skin Color Parameters and Environmental and Behavioral Factors in Estimating the Risk of Skin Cancer: A Case-Control Study.

Authors:  Marta Fijałkowska; Mateusz Koziej; Elżbieta Żądzińska; Bogusław Antoszewski; Aneta Sitek
Journal:  J Clin Med       Date:  2022-05-25       Impact factor: 4.964

Review 4.  Pathogenesis of Keratinocyte Carcinomas and the Therapeutic Potential of Medicinal Plants and Phytochemicals.

Authors:  Andrea Jess Josiah; Danielle Twilley; Sreejarani Kesavan Pillai; Suprakas Sinha Ray; Namrita Lall
Journal:  Molecules       Date:  2021-04-01       Impact factor: 4.411

5.  Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways.

Authors:  Yuhree Kim; Jie Yin; Hailiang Huang; Eric Jorgenson; Hélène Choquet; Maryam M Asgari
Journal:  Commun Biol       Date:  2022-04-21

6.  TGF-β/VEGF-A Genetic Variants Interplay in Genetic Susceptibility to Non-Melanocytic Skin Cancer.

Authors:  Letizia Scola; Maria Rita Bongiorno; Giusi Irma Forte; Anna Aiello; Giulia Accardi; Chiara Scrimali; Rossella Spina; Domenico Lio; Giuseppina Candore
Journal:  Genes (Basel)       Date:  2022-07-13       Impact factor: 4.141
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.