Literature DB >> 32434654

Therapeutic RNA Strategies for Chronic Obstructive Pulmonary Disease.

Dan Mei1, W S Daniel Tan1, Yvonne Tay2, Amartya Mukhopadhyay3, W S Fred Wong4.   

Abstract

Chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation with persistent respiratory symptoms. Current therapeutics for COPD are largely borrowed from the drug armamentarium for the treatment of asthma, which has different pathophysiological mechanisms from COPD. COPD has been linked to dysregulated expression of mRNAs and noncoding (nc)RNAs including miRNAs, PIWI-interacting (pi)RNAs, long noncoding (lnc)RNAs, and circular (circ)RNAs. This review highlights and discusses some recent advances towards development of RNA therapeutics for COPD.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  antagomir; antisense oligonucleotide; circular RNA; long noncoding RNA; miRNA; siRNA

Year:  2020        PMID： 32434654     DOI： 10.1016/j.tips.2020.04.007

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  12 in total

1.  Identification and validation of aging-related genes in COPD based on bioinformatics analysis.

Authors:  Shan Zhong; Li Yang; Naijia Liu; Guangkeng Zhou; Zhangli Hu; Chengshui Chen; Yun Wang
Journal:  Aging (Albany NY)       Date:  2022-05-24       Impact factor: 5.955

Review 2.  Advanced human-relevant in vitro pulmonary platforms for respiratory therapeutics.

Authors:  Arbel Artzy-Schnirman; Sivan Arber Raviv; Ofri Doppelt Flikshtain; Jeny Shklover; Netanel Korin; Adi Gross; Boaz Mizrahi; Avi Schroeder; Josué Sznitman
Journal:  Adv Drug Deliv Rev       Date:  2021-07-29       Impact factor: 15.470

3.  Circ-HACE1 Aggravates Cigarette Smoke Extract-Induced Injury in Human Bronchial Epithelial Cells via Regulating Toll-Like Receptor 4 by Sponging miR-485-3p.

Authors:  Fujun Zhou; Cheng Cao; Huiping Chai; Jingfang Hong; Min Zhu
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2021-06-01

Review 4.  Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects.

Authors:  You Xu; Aneesh Thakur; Yibang Zhang; Camilla Foged
Journal:  Pharmaceutics       Date:  2021-01-28       Impact factor: 6.321

5.  MiR-29c inhibits the metastasis of oral squamous cell carcinoma and promotes its cell cycle arrest by targeting SERPINH1.

Authors:  Chuanning Wang; Zhiming Wang; Liping Zhang; Xiaoping Lin
Journal:  Ann Transl Med       Date:  2021-09

6.  The Long-Noncoding RNA TUG1 Regulates Oxygen-Induced Retinal Neovascularization in Mice via MiR-299.

Authors:  Yue Wang; Xue Wang; Yue-Xia Wang; Yuan Ma; Yu Di
Journal:  Invest Ophthalmol Vis Sci       Date:  2022-01-03       Impact factor: 4.799

Review 7.  Hotspots and development frontiers of circRNA based on bibliometric analysis.

Authors:  Chunlei Zhang; Yindong Kang; Feiyan Kong; Qi Yang; Dehui Chang
Journal:  Noncoding RNA Res       Date:  2022-03-21

8.  Downregulation of miR-140-3p Contributes to Upregulation of CD38 Protein in Bronchial Smooth Muscle Cells.

Authors:  Yoshihiko Chiba; Mayumi Matsumoto; Motohiko Hanazaki; Hiroyasu Sakai
Journal:  Int J Mol Sci       Date:  2020-10-27       Impact factor: 5.923

Review 9.  Precision and Advanced Nano-Phytopharmaceuticals for Therapeutic Applications.

Authors:  Chooi Ling Lim; Chandramathi S Raju; Tooba Mahboob; Sunil Kayesth; Kamal K Gupta; Gaurav Kumar Jain; Mahaveer Dhobi; Muhammad Nawaz; Polrat Wilairatana; Maria de Lourdes Pereira; Jayanta Kumar Patra; Alok K Paul; Mohammed Rahmatullah; Veeranoot Nissapatorn
Journal:  Nanomaterials (Basel)       Date:  2022-01-12       Impact factor: 5.076

Review 10.  Targeting Inflammasome Activation in COVID-19: Delivery of RNA Interference-Based Therapeutic Molecules.

Authors:  Lealem Gedefaw; Sami Ullah; Thomas M H Lee; Shea Ping Yip; Chien-Ling Huang
Journal:  Biomedicines       Date:  2021-12-03
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