Literature DB >> 32431422

Organ Donation and Declaration of Death: Combined Neurologic and Cardiopulmonary Standards.

Stephen E Doran1, Joseph M Vukov2.   

Abstract

Prolonged survival after the declaration of death by neurologic criteria creates ambiguity regarding the validity of this methodology. This ambiguity has perpetuated the debate among secular and nondissenting Catholic authors who question whether the neurologic standards are sufficient for the declaration of death of organ donors. Cardiopulmonary criteria are being increasingly used for organ donors who do not meet brain death standards. However, cardiopulmonary criteria are plagued by conflict of interest issues, arbitrary standards for candidacy, and the lack of standardized protocols for organ procurement. Combining the neurological and cardiopulmonary standards into a single protocol would mitigate the weaknesses of both and provide greater biologic and moral certainty that a donor of unpaired vital organs is indeed dead.
SUMMARY: Before a person's organs can be used for transplantation, he or she must be declared "brain-dead." However, sometimes when someone is declared brain-dead, that person can be maintained on life-support for days or even weeks. This creates some confusion about whether the person has truly died. For patients who have a severe neurologic injury but are not brain-dead, organ donation can also occur after his or her heart stops beating. However, this protocol is more ambiguous and lacks standardized protocols. We propose that before a person can donate organs, he or she must first be declared brain-dead, and then his or her heart must irreversibly stop beating before organs are taken. © Catholic Medical Association 2019.

Entities:  

Keywords:  Bodily integration; Brain death; Cardiopulmonary criteria; DCD; Organ donation

Year:  2019        PMID: 32431422      PMCID: PMC6880078          DOI: 10.1177/0024363919840129

Source DB:  PubMed          Journal:  Linacre Q        ISSN: 0024-3639


  16 in total

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2.  Total brain death: a reply to Alan Shewmon.

Authors:  Patrick Lee; Germain GriseZ
Journal:  Bioethics       Date:  2012-06       Impact factor: 1.898

3.  Donation after cardiac death: a 29-year experience.

Authors:  Janet M Bellingham; Chandrasekar Santhanakrishnan; Nikole Neidlinger; Philip Wai; Jim Kim; Silke Niederhaus; Glen E Leverson; Luis A Fernandez; David P Foley; Joshua D Mezrich; Jon S Odorico; Robert B Love; Nilto De Oliveira; Hans W Sollinger; Anthony M D'Alessandro
Journal:  Surgery       Date:  2011-10       Impact factor: 3.982

4.  Long survival following bacterial meningitis-associated brain destruction.

Authors:  Susan Repertinger; William P Fitzgibbons; Mathew F Omojola; Roger A Brumback
Journal:  J Child Neurol       Date:  2006-07       Impact factor: 1.987

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Authors:  Melissa Moschella
Journal:  J Med Philos       Date:  2016-04-23

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Authors:  Robert D Truog; Franklin G Miller
Journal:  Am J Bioeth       Date:  2014       Impact factor: 11.229

7.  Brain dead patients are still whole organisms.

Authors:  Nicholas Sadovnikoff; Daniel Wikler
Journal:  Am J Bioeth       Date:  2014       Impact factor: 11.229

8.  A definition of irreversible coma. Report of the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death.

Authors: 
Journal:  JAMA       Date:  1968-08-05       Impact factor: 56.272

9.  Variability of Brain Death Policies in the United States.

Authors:  David M Greer; Hilary H Wang; Jennifer D Robinson; Panayiotis N Varelas; Galen V Henderson; Eelco F M Wijdicks
Journal:  JAMA Neurol       Date:  2016-02       Impact factor: 18.302

10.  Pediatric heart transplantation after declaration of cardiocirculatory death.

Authors:  Mark M Boucek; Christine Mashburn; Susan M Dunn; Rebecca Frizell; Leah Edwards; Biagio Pietra; David Campbell
Journal:  N Engl J Med       Date:  2008-08-14       Impact factor: 91.245

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  1 in total

1.  Double Effect Donation.

Authors:  Charles C Camosy; Joseph Vukov
Journal:  Linacre Q       Date:  2021-02-08
  1 in total

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