Literature DB >> 32429998

Correction to: Astaxanthin-loaded polymer-lipid hybrid nanoparticles (ATX-LPN): assessment of potential otoprotective effects.

Jiayi Gu1,2,3, Yuming Chen1,2,3, Ling Tong1,2,3, Xueling Wang4,5,6, Dehong Yu7,8,9, Hao Wu10,11,12.   

Abstract

An amendment to this paper has been published and can be accessed via the original article.

Entities:  

Year:  2020        PMID: 32429998      PMCID: PMC7236955          DOI: 10.1186/s12951-020-00627-0

Source DB:  PubMed          Journal:  J Nanobiotechnology        ISSN: 1477-3155            Impact factor:   10.435


Correction to: J Nanobiotechnol (2020) 18:53 10.1186/s12951-020-00600-x

Following publication of the original article [1], the authors identified errors in Fig. 8d and f. The corrected Fig. 8 and the corrected figure caption are given below.
Fig. 8

ATX-LPN partially rescue CDDP-induced hearing loss. a In vitro culture of Organ of Corti. CDDP induced a significant loss of hair cells (Myosin VII, red), especially in the high-frequency areas. b Survival outer hair cell numbers in 1 mm length at different locations from apical end of each group. *p < 0.05, **p < 0.01, ***p < 0.001 as compared with CDDP, #p < 0.05 as compared with ATX + CDDP. c–e Mean ABR threshold of mice treated with cisplatin, ATX 1 mg/ml, 5 μl. ATX-LPN + CDDP. *p < 0.05, **p < 0.01, ***p < 0.001 as compared with CDDP, #p < 0.05 as compared with ATX + CDDP. f Immunohistochemistry of cochlea in apex/middle/basal area of BM. The pretreatment of protective drugs (ATX/ATX-LPN) effectively reduced the expression of caspase-3 (red fluorescence) and rescued more OHCs (green fluorescence)

ATX-LPN partially rescue CDDP-induced hearing loss. a In vitro culture of Organ of Corti. CDDP induced a significant loss of hair cells (Myosin VII, red), especially in the high-frequency areas. b Survival outer hair cell numbers in 1 mm length at different locations from apical end of each group. *p < 0.05, **p < 0.01, ***p < 0.001 as compared with CDDP, #p < 0.05 as compared with ATX + CDDP. c–e Mean ABR threshold of mice treated with cisplatin, ATX 1 mg/ml, 5 μl. ATX-LPN + CDDP. *p < 0.05, **p < 0.01, ***p < 0.001 as compared with CDDP, #p < 0.05 as compared with ATX + CDDP. f Immunohistochemistry of cochlea in apex/middle/basal area of BM. The pretreatment of protective drugs (ATX/ATX-LPN) effectively reduced the expression of caspase-3 (red fluorescence) and rescued more OHCs (green fluorescence)
  1 in total

1.  Astaxanthin-loaded polymer-lipid hybrid nanoparticles (ATX-LPN): assessment of potential otoprotective effects.

Authors:  Jiayi Gu; Yuming Chen; Ling Tong; Xueling Wang; Dehong Yu; Hao Wu
Journal:  J Nanobiotechnology       Date:  2020-03-19       Impact factor: 10.435

  1 in total
  1 in total

Review 1.  Nanomaterials for Inner Ear Diseases: Challenges, Limitations and Opportunities.

Authors:  Liling Li; Jia Luo; Xuexin Lin; Jingqian Tan; Peng Li
Journal:  Materials (Basel)       Date:  2022-05-25       Impact factor: 3.748

  1 in total

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