S Ali Husain1,2, Geoffrey Dube3, Heather Morris3, Hilda Fernandez3, Jae-Hyung Chang3, Kathryn Paget3, Sharlinee Sritharan3, Shefali Patel3, Olga Pawliczak3, Mia Boehler3, Demetra Tsapepas2,4, R John Crew3, David J Cohen3, Sumit Mohan3,2,5. 1. Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons and New York Presbyterian Hospital, New York, New York SAH2134@cumc.columbia.edu. 2. The Columbia University Renal Epidemiology Group, New York, New York. 3. Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons and New York Presbyterian Hospital, New York, New York. 4. New York-Presbyterian Hospital, New York, New York. 5. Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Abstract
BACKGROUND AND OBJECTIVES: Outcomes of kidney transplant recipients diagnosed with coronavirus disease 2019 as outpatients have not been described. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We obtained clinical data for 41 consecutive outpatient kidney transplant recipients with known or suspected coronavirus disease 2019. Chi-squared and Wilcoxon rank sum tests were used to compare characteristics of patients who required hospitalization versus those who did not. RESULTS: Of 41 patients, 22 (54%) had confirmed coronavirus disease 2019, and 19 (46%) were suspected cases. Patients most commonly reported fever (80%), cough (56%), and dyspnea (39%). At the end of follow-up, 13 patients (32%) required hospitalization a median of 8 days (range, 1-16) after symptom onset, and 23 (56%) had outpatient symptom resolution a median of 12 days (4-23) after onset. Patients who required hospitalization were more likely to have reported dyspnea (77% versus 21%, P=0.003) and had higher baseline creatinine (median, 2.0 versus 1.3 mg/dl, P=0.02), but there were no other differences between groups. CONCLUSIONS: In an early cohort of outpatient kidney transplant recipients with known or suspected coronavirus disease 2019, many had symptomatic resolution without requiring hospitalization.
BACKGROUND AND OBJECTIVES: Outcomes of kidney transplant recipients diagnosed with coronavirus disease 2019 as outpatients have not been described. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We obtained clinical data for 41 consecutive outpatient kidney transplant recipients with known or suspected coronavirus disease 2019. Chi-squared and Wilcoxon rank sum tests were used to compare characteristics of patients who required hospitalization versus those who did not. RESULTS: Of 41 patients, 22 (54%) had confirmed coronavirus disease 2019, and 19 (46%) were suspected cases. Patients most commonly reported fever (80%), cough (56%), and dyspnea (39%). At the end of follow-up, 13 patients (32%) required hospitalization a median of 8 days (range, 1-16) after symptom onset, and 23 (56%) had outpatient symptom resolution a median of 12 days (4-23) after onset. Patients who required hospitalization were more likely to have reported dyspnea (77% versus 21%, P=0.003) and had higher baseline creatinine (median, 2.0 versus 1.3 mg/dl, P=0.02), but there were no other differences between groups. CONCLUSIONS: In an early cohort of outpatient kidney transplant recipients with known or suspected coronavirus disease 2019, many had symptomatic resolution without requiring hospitalization.
Authors: Natacha S Ogando; Erik Metscher; Dirk Jan A R Moes; Eline J Arends; Ali Tas; Jennifer Cross; Eric J Snijder; Y K Onno Teng; Aiko P J de Vries; Martijn J van Hemert Journal: Transpl Int Date: 2022-06-24 Impact factor: 3.842
Authors: Marcus R Pereira; Selim Arcasoy; Maryjane A Farr; Sumit Mohan; Jean C Emond; Demetra S Tsapepas; Qiuhu Shi; Lawrence Purpura; Anne-Catrin Uhlemann; Jason Zucker; Elizabeth C Verna Journal: Transpl Infect Dis Date: 2021-05-31
Authors: John M Søfteland; Gustav Friman; Bengt von Zur-Mühlen; Bo-Göran Ericzon; Carin Wallquist; Kristjan Karason; Vanda Friman; Jan Ekelund; Marie Felldin; Jesper Magnusson; Ida Haugen Löfman; Andreas Schult; Emily de Coursey; Susannah Leach; Hanna Jacobsson; Jan-Åke Liljeqvist; Ali R Biglarnia; Per Lindnér; Mihai Oltean Journal: Am J Transplant Date: 2021-05-06 Impact factor: 9.369
Authors: Muhammad Y Jan; Skye E Sayegh; Hanna T Webb; Oluwafisayo Adebiyi; Melissa D Anderson; Dennis P Mishler; Muhammad S Yaqub; Tim Taber; Asif A Sharfuddin Journal: Kidney Int Rep Date: 2021-06-26