Stefano Olmi1, Matteo Uccelli2, Giovanni Carlo Cesana3, Francesca Ciccarese3, Alberto Oldani3, Riccardo Giorgi3, Stefano Maria De Carli3, Roberta Villa3. 1. General and Oncologic Surgery Department, Centre of Bariatric Surgery, San Marco Hospital GSD, Zingonia, Italy; University of Milan and Vita-Salute University San Raffaele, Milan, Italy. 2. General and Oncologic Surgery Department, Centre of Bariatric Surgery, San Marco Hospital GSD, Zingonia, Italy. Electronic address: matteo.uccelli@gmail.com. 3. General and Oncologic Surgery Department, Centre of Bariatric Surgery, San Marco Hospital GSD, Zingonia, Italy.
Abstract
BACKGROUND: Gastroesophageal reflux disease (GERD), including erosive esophagitis, is highly prevalent in the obese population. Laparoscopic sleeve gastrectomy (LSG) is one of the most frequently performed bariatric procedures. The relationship between LSG and GERD has gained increasing attention. This retrospective study aimed to assess the effectiveness of combined LSG and modified Rossetti antireflux fundoplication for the treatment of GERD on morbidly obese patients after bariatric surgery. OBJECTIVES: To assess the effectiveness, on morbid obese patients, of combined SG and Rossetti fundoplication for the treatment of GERD in obese patients. SETTING: Public Hospital, Italy. METHODS: From January 2015 to May 2018, 220 obese patients (167 female; 53 male) underwent LSG and modified Rossetti antireflux fundoplication procedure, performed by 4 different expert bariatric surgeons. Data have been collected in an Excel file and processed by XLStat to perform statistical analyses. We analyzed short-term complications and medium-term results with 24-month follow-up in terms of weight loss, remission of co-morbidities, and resolution of GERD. RESULTS: Mean BMI was 42.58 ± 5.93 kg/m2 (range, 31.70-63.16). Patients suffering from GERD before surgery were 137 of 220 (62.3%). No intraoperative complications or conversion were reported. Regular postoperative course was recorded in 90% of patients (198 of 220 patients). Gastric perforation has always occurred on the fundoplicated portion of the stomach. This perforation, which is different from the well-known post-LSG gastric fistula, may be because of incorrect gastric fundus manipulation. Rate of reoperation was 14 of 220 (6.4%). A good sense of repletion without episodes of vomiting, nausea, or dysphagia was reported in 95% of the analyzed patients. Of patients, 98.5% did not suffer from reflux symptoms and did not take proton pump inhibitors. A decrease in BMI and percent of total weight loss at follow-up were comparable with LSG. Endoscopic follow-up is still ongoing. Improvement in esophagitis was observed in 63 of 65 (96.92%) patients and all 4 patients shows improvement in Barrett's esophagus. CONCLUSIONS: LSG and modified Rossetti antireflux fundoplication procedure is a tolerated and feasible procedure in obese patients, with good postoperative weight loss results and improvement in GERD.
BACKGROUND:Gastroesophageal reflux disease (GERD), including erosive esophagitis, is highly prevalent in the obese population. Laparoscopic sleeve gastrectomy (LSG) is one of the most frequently performed bariatric procedures. The relationship between LSG and GERD has gained increasing attention. This retrospective study aimed to assess the effectiveness of combined LSG and modified Rossetti antireflux fundoplication for the treatment of GERD on morbidly obesepatients after bariatric surgery. OBJECTIVES: To assess the effectiveness, on morbid obesepatients, of combined SG and Rossetti fundoplication for the treatment of GERD in obesepatients. SETTING: Public Hospital, Italy. METHODS: From January 2015 to May 2018, 220 obesepatients (167 female; 53 male) underwent LSG and modified Rossetti antireflux fundoplication procedure, performed by 4 different expert bariatric surgeons. Data have been collected in an Excel file and processed by XLStat to perform statistical analyses. We analyzed short-term complications and medium-term results with 24-month follow-up in terms of weight loss, remission of co-morbidities, and resolution of GERD. RESULTS: Mean BMI was 42.58 ± 5.93 kg/m2 (range, 31.70-63.16). Patients suffering from GERD before surgery were 137 of 220 (62.3%). No intraoperative complications or conversion were reported. Regular postoperative course was recorded in 90% of patients (198 of 220 patients). Gastric perforation has always occurred on the fundoplicated portion of the stomach. This perforation, which is different from the well-known post-LSG gastric fistula, may be because of incorrect gastric fundus manipulation. Rate of reoperation was 14 of 220 (6.4%). A good sense of repletion without episodes of vomiting, nausea, or dysphagia was reported in 95% of the analyzed patients. Of patients, 98.5% did not suffer from reflux symptoms and did not take proton pump inhibitors. A decrease in BMI and percent of total weight loss at follow-up were comparable with LSG. Endoscopic follow-up is still ongoing. Improvement in esophagitis was observed in 63 of 65 (96.92%) patients and all 4 patients shows improvement in Barrett's esophagus. CONCLUSIONS: LSG and modified Rossetti antireflux fundoplication procedure is a tolerated and feasible procedure in obesepatients, with good postoperative weight loss results and improvement in GERD.
Authors: Judith W H 't Hart; Bo J Noordman; Laser U Biter; Ivonne Leeuwenburgh; Martin Dunkelgrun; Jan A Apers Journal: BMJ Open Date: 2022-06-10 Impact factor: 3.006