L Grevillot1, D J Boersma1,2, H Fuchs1,3,4, A Aitkenhead5, A Elia1, M Bolsa1, C Winterhalter6, M Vidal7, S Jan8, U Pietrzyk9, L Maigne10, D Sarrut11. 1. MedAustron Ion Therapy Center, Marie Curie-Straße 5, A-2700, Wiener Neustadt, Austria. 2. ACMIT Gmbh, Viktor-Kaplan-Straße 2/1, A-2700, Wiener Neustadt, Austria. 3. Medical University of Vienna, Vienna, Austria. 4. Department of Radiation Therapy, Medical University of Vienna/AKH Vienna, Vienna, Austria. 5. Division of Cancer Sciences, University of Manchester, Manchester Cancer Research Centre, The Christie NHS Foundation Trust, Manchester, UK. 6. Division of Cancer Sciences, University of Manchester, The Christie NHS Foundation Trust, Manchester, UK. 7. Centre Antoine LACASSAGNE, Université Côte d'Azur - Fédération Claude Lalanne, Nice, France. 8. UMR BioMaps, CEA, CNRS, Inserm, Université Paris-Saclay, 4 place du Général Leclerc, 91401, Orsay, France. 9. University of Wuppertal, Wuppertal, Germany. 10. Université Clermont Auvergne, CNRS/IN2P3, Laboratoire de Physique de Clermont, UMR6533, 4 avenue Blaise Pascal TSA 60026 CS, 60026 63178, Aubière cedex, France. 11. Université de Lyon, CREATIS, CNRS UMR5220, Inserm U1044, INSA-Lyon, Université Lyon 1, Lyon, France.
Abstract
PURPOSE: GATE-RTion is a validated version of GATE for clinical use in the field of light ion beam therapy. This paper describes the GATE-RTion project and illustrates its potential through clinical applications developed in three European centers delivering scanned proton and carbon ion treatments. METHODS: GATE-RTion is a collaborative framework provided by the OpenGATE collaboration. It contains a validated GATE release based on a specific Geant4 version, a set of tools to integrate GATE into a clinical environment and a network for clinical users. RESULTS: Three applications are presented: Proton radiography at the Centre Antoine Lacassagne (Nice, France); Independent dose calculation for proton therapy at the Christie NHS Foundation Trust (Manchester, UK); Independent dose calculation for protons and carbon ions at the MedAustron Ion Therapy center (Wiener Neustadt, Austria). CONCLUSIONS: GATE-RTion builds the bridge between researchers and clinical users from the OpenGATE collaboration in the field of Light Ion Beam Therapy. The applications presented in three European facilities using three completely different machines (three different vendors, cyclotron- and synchrotron-based systems, protons, and carbon ions) demonstrate the relevance and versatility of this project.
PURPOSE: GATE-RTion is a validated version of GATE for clinical use in the field of light ion beam therapy. This paper describes the GATE-RTion project and illustrates its potential through clinical applications developed in three European centers delivering scanned proton and carbon ion treatments. METHODS: GATE-RTion is a collaborative framework provided by the OpenGATE collaboration. It contains a validated GATE release based on a specific Geant4 version, a set of tools to integrate GATE into a clinical environment and a network for clinical users. RESULTS: Three applications are presented: Proton radiography at the Centre Antoine Lacassagne (Nice, France); Independent dose calculation for proton therapy at the Christie NHS Foundation Trust (Manchester, UK); Independent dose calculation for protons and carbon ions at the MedAustron Ion Therapy center (Wiener Neustadt, Austria). CONCLUSIONS: GATE-RTion builds the bridge between researchers and clinical users from the OpenGATE collaboration in the field of Light Ion Beam Therapy. The applications presented in three European facilities using three completely different machines (three different vendors, cyclotron- and synchrotron-based systems, protons, and carbon ions) demonstrate the relevance and versatility of this project.
Authors: Adam H Aitkenhead; Peter Sitch; Jenny C Richardson; Carla Winterhalter; Imran Patel; Ranald I Mackay Journal: Br J Radiol Date: 2020-07-29 Impact factor: 3.039
Authors: Liyong Lin; Paige A Taylor; Jiajian Shen; Jatinder Saini; Minglei Kang; Charles B Simone; Jeffrey D Bradley; Zuofeng Li; Ying Xiao Journal: Int J Part Ther Date: 2021-05-25
Authors: Andreas Franz Resch; Mansure Schafasand; Niklas Lackner; Tom Niessen; Staffan Beck; Alessio Elia; David Boersma; Loïc Grevillot; Piero Fossati; Lars Glimelius; Markus Stock; Dietmar Georg; Antonio Carlino Journal: Med Phys Date: 2022-04-27 Impact factor: 4.506